| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the rofecoxib-256 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALOX12 | arachidonate 12-lipoxygenase |
| APOL6 | apolipoprotein L, 6 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| AXIN1 | axin 1 |
| BHMT | betaine--homocysteine S-methyltransferase |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C21ORF62 | chromosome 21 open reading frame 62 |
| CA6 | carbonic anhydrase VI |
| CADM3 | cell adhesion molecule 3 |
| CAPN9 | calpain 9 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCNT2 | cyclin T2 |
| CEP41 | centrosomal protein 41kDa |
| CLIC5 | chloride intracellular channel 5 |
| COX5B | cytochrome c oxidase subunit Vb |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DAPK2 | death-associated protein kinase 2 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
| DIO2 | deiodinase, iodothyronine, type II |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUS2 | dihydrouridine synthase 2 |
| ESR2 | estrogen receptor 2 (ER beta) |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM184A | family with sequence similarity 184, member A |
| FCAR | Fc fragment of IgA receptor |
| FDX1 | ferredoxin 1 |
| G0S2 | G0/G1 switch 2 |
| GAB1 | GRB2-associated binding protein 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GFRA3 | GDNF family receptor alpha 3 |
| GMPR | guanosine monophosphate reductase |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| HOXD1 | homeobox D1 |
| HSPB11 | heat shock protein family B (small), member 11 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL11 | interleukin 11 |
| IQCG | IQ motif containing G |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KNG1 | kininogen 1 |
| KRT5 | keratin 5, type II |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAOA | monoamine oxidase A |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MCOLN3 | mucolipin 3 |
| MMP19 | matrix metallopeptidase 19 |
| MST1 | macrophage stimulating 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTMR2 | myotubularin related protein 2 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NDRG2 | NDRG family member 2 |
| NGLY1 | N-glycanase 1 |
| NPHP4 | nephronophthisis 4 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUPL2 | nucleoporin like 2 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PLK4 | polo-like kinase 4 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHO | rhodopsin |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| RNF141 | ring finger protein 141 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| RUFY3 | RUN and FYVE domain containing 3 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SFTPC | surfactant protein C |
| SLC38A7 | solute carrier family 38, member 7 |
| SON | SON DNA binding protein |
| SP100 | SP100 nuclear antigen |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TBX5 | T-box 5 |
| TCP11 | t-complex 11, testis-specific |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TLN2 | talin 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM176A | transmembrane protein 176A |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNS2 | tensin 2 |
| TTC26 | tetratricopeptide repeat domain 26 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZNF358 | zinc finger protein 358 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AICDA | activation-induced cytidine deaminase |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AMPH | amphiphysin |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| BARX2 | BARX homeobox 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C4BPA | complement component 4 binding protein, alpha |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CCDC85C | coiled-coil domain containing 85C |
| CCNK | cyclin K |
| CD38 | CD38 molecule |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CELA3B | chymotrypsin-like elastase family, member 3B |
| CHGA | chromogranin A |
| CLC | Charcot-Leyden crystal galectin |
| CLPS | colipase, pancreatic |
| CNPY3 | canopy FGF signaling regulator 3 |
| CORT | cortistatin |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CTF1 | cardiotrophin 1 |
| CUEDC1 | CUE domain containing 1 |
| CXXC4 | CXXC finger protein 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGKZ | diacylglycerol kinase, zeta |
| DKFZP434C153 | DKFZP434C153 protein |
| DRP2 | dystrophin related protein 2 |
| DYSF | dysferlin |
| ECE2 | endothelin converting enzyme 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FMO6P | flavin containing monooxygenase 6 pseudogene |
| FN3K | fructosamine 3 kinase |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMD1 | FERM domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR27 | G protein-coupled receptor 27 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GYPC | glycophorin C (Gerbich blood group) |
| HBD | hemoglobin, delta |
| HOXB1 | homeobox B1 |
| HOXB2 | homeobox B2 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFFO1 | intermediate filament family orphan 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INE1 | inactivation escape 1 (non-protein coding) |
| IRF8 | interferon regulatory factor 8 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNC4 | potassium channel, voltage gated Shaw related subfamily C, member 4 |
| KRT75 | keratin 75, type II |
| LAMA3 | laminin, alpha 3 |
| LIN28A | lin-28 homolog A (C. elegans) |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D |
| MAPK3 | mitogen-activated protein kinase 3 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| NXF2 | nuclear RNA export factor 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PCDHB6 | protocadherin beta 6 |
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| PGK2 | phosphoglycerate kinase 2 |
| PHOX2A | paired-like homeobox 2a |
| PI15 | peptidase inhibitor 15 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PRDM14 | PR domain containing 14 |
| PRMT7 | protein arginine methyltransferase 7 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| PYGM | phosphorylase, glycogen, muscle |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RGR | retinal G protein coupled receptor |
| RIN2 | Ras and Rab interactor 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPAG4 | sperm associated antigen 4 |
| SQRDL | sulfide quinone reductase-like (yeast) |
| SSTR4 | somatostatin receptor 4 |
| ST7L | suppression of tumorigenicity 7 like |
| TH | tyrosine hydroxylase |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM132A | transmembrane protein 132A |
| TRPV5 | transient receptor potential cation channel, subfamily V, member 5 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VEGFB | vascular endothelial growth factor B |
