| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the rofecoxib-371 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALOX5 | arachidonate 5-lipoxygenase |
| APOA1 | apolipoprotein A-I |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ATG2A | autophagy related 2A |
| AXIN1 | axin 1 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CA12 | carbonic anhydrase XII |
| CALHM2 | calcium homeostasis modulator 2 |
| CAMKV | CaM kinase-like vesicle-associated |
| CAV3 | caveolin 3 |
| CDC42 | cell division cycle 42 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CLEC1B | C-type lectin domain family 1, member B |
| CLIC5 | chloride intracellular channel 5 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CYB561 | cytochrome b561 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FGF4 | fibroblast growth factor 4 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| FOXA1 | forkhead box A1 |
| GAS8-AS1 | GAS8 antisense RNA 1 |
| GDF11 | growth differentiation factor 11 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR153 | G protein-coupled receptor 153 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| ICAM2 | intercellular adhesion molecule 2 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL1RN | interleukin 1 receptor antagonist |
| IRGQ | immunity-related GTPase family, Q |
| KCNJ9 | potassium channel, inwardly rectifying subfamily J, member 9 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LOC729164 | hCG1732469 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MST1 | macrophage stimulating 1 |
| MT4 | metallothionein 4 |
| MYL10 | myosin, light chain 10, regulatory |
| MYT1 | myelin transcription factor 1 |
| NAA60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OMG | oligodendrocyte myelin glycoprotein |
| PAX1 | paired box 1 |
| PDCD2 | programmed cell death 2 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PKN1 | protein kinase N1 |
| PLD2 | phospholipase D2 |
| PRDX2 | peroxiredoxin 2 |
| PTGES | prostaglandin E synthase |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB15 | RAB15, member RAS oncogene family |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF121 | ring finger protein 121 |
| RPL13 | ribosomal protein L13 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SH3BP2 | SH3-domain binding protein 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPN | sialophorin |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TESK2 | testis-specific kinase 2 |
| TLR6 | toll-like receptor 6 |
| TNF | tumor necrosis factor |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TRD | T cell receptor delta locus |
| TRMT61A | tRNA methyltransferase 61A |
| TUBA4B | tubulin, alpha 4b |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZNF473 | zinc finger protein 473 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABHD3 | abhydrolase domain containing 3 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANKRD11 | ankyrin repeat domain 11 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC109B | coiled-coil domain containing 109B |
| CCDC53 | coiled-coil domain containing 53 |
| CELA3B | chymotrypsin-like elastase family, member 3B |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COG4 | component of oligomeric golgi complex 4 |
| COQ3 | coenzyme Q3 methyltransferase |
| CRYAB | crystallin, alpha B |
| DDX47 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| E2F6 | E2F transcription factor 6 |
| EHBP1 | EH domain binding protein 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FZD4 | frizzled class receptor 4 |
| GJB1 | gap junction protein, beta 1, 32kDa |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble |
| HAGH | hydroxyacylglutathione hydrolase |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HPGDS | hematopoietic prostaglandin D synthase |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL10 | interleukin 10 |
| IL4R | interleukin 4 receptor |
| ITGB7 | integrin, beta 7 |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 |
| KIF21B | kinesin family member 21B |
| KLHL12 | kelch-like family member 12 |
| KRT1 | keratin 1, type II |
| KRT32 | keratin 32, type I |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) |
| LHX6 | LIM homeobox 6 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LMAN2L | lectin, mannose-binding 2-like |
| LUZP4 | leucine zipper protein 4 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMP8 | matrix metallopeptidase 8 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NCS1 | neuronal calcium sensor 1 |
| NKG7 | natural killer cell granule protein 7 |
| NOP14 | NOP14 nucleolar protein |
| OARD1 | O-acyl-ADP-ribose deacylase 1 |
| PADI2 | peptidyl arginine deiminase, type II |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCTP | phosphatidylcholine transfer protein |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLVAP | plasmalemma vesicle associated protein |
| PRKCE | protein kinase C, epsilon |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RBP1 | retinol binding protein 1, cellular |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RWDD3 | RWD domain containing 3 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SH3BP1 | SH3-domain binding protein 1 |
| SIX6 | SIX homeobox 6 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| SST | somatostatin |
| STRA13 | stimulated by retinoic acid 13 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFB3 | transforming growth factor, beta 3 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TMEM127 | transmembrane protein 127 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM32 | tripartite motif containing 32 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| WDR11 | WD repeat domain 11 |
| WRB | tryptophan rich basic protein |
| WT1-AS | WT1 antisense RNA |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF107 | zinc finger protein 107 |
| ZNF443 | zinc finger protein 443 |
| ZNF480 | zinc finger protein 480 |
| ZNF557 | zinc finger protein 557 |
