| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the rofecoxib-463 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACAN | aggrecan |
| ACRV1 | acrosomal vesicle protein 1 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AFF1 | AF4/FMR2 family, member 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AMT | aminomethyltransferase |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASF1A | anti-silencing function 1A histone chaperone |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| AVPR1B | arginine vasopressin receptor 1B |
| BGN | biglycan |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| CAPN3 | calpain 3, (p94) |
| CAV3 | caveolin 3 |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD53 | CD53 molecule |
| CD8A | CD8a molecule |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CELF2 | CUGBP, Elav-like family member 2 |
| CETN1 | centrin, EF-hand protein, 1 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLEC11A | C-type lectin domain family 11, member A |
| COQ3 | coenzyme Q3 methyltransferase |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CST4 | cystatin S |
| DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 |
| DTNA | dystrobrevin, alpha |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FGF4 | fibroblast growth factor 4 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HERC2P3 | hect domain and RLD 2 pseudogene 3 |
| HHIPL2 | HHIP-like 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL10RA | interleukin 10 receptor, alpha |
| IL13 | interleukin 13 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IRF2 | interferon regulatory factor 2 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KYNU | kynureninase |
| LHX3 | LIM homeobox 3 |
| LOC647070 | uncharacterized LOC647070 |
| LOC729164 | hCG1732469 |
| LUZP4 | leucine zipper protein 4 |
| LY86 | lymphocyte antigen 86 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MED31 | mediator complex subunit 31 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| NCS1 | neuronal calcium sensor 1 |
| NRXN1 | neurexin 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PADI2 | peptidyl arginine deiminase, type II |
| PIGR | polymeric immunoglobulin receptor |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLAGL2 | pleiomorphic adenoma gene-like 2 |
| PLIN2 | perilipin 2 |
| PON3 | paraoxonase 3 |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RARB | retinoic acid receptor, beta |
| RET | ret proto-oncogene |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SFTPB | surfactant protein B |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like |
| SYNGR1 | synaptogyrin 1 |
| SYT13 | synaptotagmin XIII |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D16 | TBC1 domain family, member 16 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TRIM14 | tripartite motif containing 14 |
| TSPYL2 | TSPY-like 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZNF276 | zinc finger protein 276 |
| ZNF576 | zinc finger protein 576 |
| Symbol | Name |
|---|---|
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase |
| ANKRD40 | ankyrin repeat domain 40 |
| ATXN2 | ataxin 2 |
| BLMH | bleomycin hydrolase |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| BTBD2 | BTB (POZ) domain containing 2 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDK9 | cyclin-dependent kinase 9 |
| CLDN17 | claudin 17 |
| COL19A1 | collagen, type XIX, alpha 1 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DPYD | dihydropyrimidine dehydrogenase |
| EDC4 | enhancer of mRNA decapping 4 |
| EFNA1 | ephrin-A1 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ESM1 | endothelial cell-specific molecule 1 |
| ETV4 | ets variant 4 |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FGF6 | fibroblast growth factor 6 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GLRA2 | glycine receptor, alpha 2 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HOXA4 | homeobox A4 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IL25 | interleukin 25 |
| JRKL | JRK-like |
| JUNB | jun B proto-oncogene |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KDR | kinase insert domain receptor |
| KIFC1 | kinesin family member C1 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGT1 | magnesium transporter 1 |
| MED9 | mediator complex subunit 9 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MON1B | MON1 secretory trafficking family member B |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYL12B | myosin, light chain 12B, regulatory |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PISD | phosphatidylserine decarboxylase |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLM | polymerase (DNA directed), mu |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRSS50 | protease, serine, 50 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| RAD54L | RAD54-like (S. cerevisiae) |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RPE | ribulose-5-phosphate-3-epimerase |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 5 |
| SMYD5 | SMYD family member 5 |
| SNX10 | sorting nexin 10 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| STXBP3 | syntaxin binding protein 3 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THOC6 | THO complex 6 |
| TLN1 | talin 1 |
| TMEM127 | transmembrane protein 127 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM58 | tripartite motif containing 58 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| UBA3 | ubiquitin-like modifier activating enzyme 3 |
| UBXN6 | UBX domain protein 6 |
| XPA | xeroderma pigmentosum, complementation group A |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF189 | zinc finger protein 189 |
| ZNF324 | zinc finger protein 324 |
