rolipram-3072 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the rolipram-3072 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADORA3 adenosine A3 receptor
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMACR alpha-methylacyl-CoA racemase
AREG amphiregulin
ARL4C ADP-ribosylation factor-like 4C
BTC betacellulin
C21ORF2 chromosome 21 open reading frame 2
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CCL22 chemokine (C-C motif) ligand 22
CCL27 chemokine (C-C motif) ligand 27
CD2 CD2 molecule
CFAP45 cilia and flagella associated protein 45
CLIP4 CAP-GLY domain containing linker protein family, member 4
CREM cAMP responsive element modulator
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSF cathepsin F
DLG4 discs, large homolog 4 (Drosophila)
DMP1 dentin matrix acidic phosphoprotein 1
DMRT1 doublesex and mab-3 related transcription factor 1
DNAH17 dynein, axonemal, heavy chain 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCR4 Down syndrome critical region 4
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
F12 coagulation factor XII (Hageman factor)
FBXO40 F-box protein 40
FGF23 fibroblast growth factor 23
FKBP5 FK506 binding protein 5
FPR1 formyl peptide receptor 1
FSCN3 fascin actin-bundling protein 3, testicular
GAS8 growth arrest-specific 8
GMPR guanosine monophosphate reductase
GRIK5 glutamate receptor, ionotropic, kainate 5
HDAC7 histone deacetylase 7
HEXIM1 hexamethylene bis-acetamide inducible 1
HRASLS2 HRAS-like suppressor 2
IFITM1 interferon induced transmembrane protein 1
IGHMBP2 immunoglobulin mu binding protein 2
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL7R interleukin 7 receptor
KRT8 keratin 8, type II
LAMB3 laminin, beta 3
LMF1 lipase maturation factor 1
LOC100287590 uncharacterized LOC100287590
LOC257152 uncharacterized LOC257152
LTBP1 latent transforming growth factor beta binding protein 1
MCTP2 multiple C2 domains, transmembrane 2
MED22 mediator complex subunit 22
MSX2 msh homeobox 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD4 MAX dimerization protein 4
MYL10 myosin, light chain 10, regulatory
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NTF3 neurotrophin 3
PBX2 pre-B-cell leukemia homeobox 2
PCDH8 protocadherin 8
PER1 period circadian clock 1
PID1 phosphotyrosine interaction domain containing 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGES prostaglandin E synthase
PVR poliovirus receptor
RAB6B RAB6B, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RELN reelin
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SDC2 syndecan 2
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SH3GL3 SH3-domain GRB2-like 3
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPAG8 sperm associated antigen 8
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST14 suppression of tumorigenicity 14 (colon carcinoma)
SYT2 synaptotagmin II
SYTL2 synaptotagmin-like 2
TEAD3 TEA domain family member 3
THBS1 thrombospondin 1
TK2 thymidine kinase 2, mitochondrial
TLR6 toll-like receptor 6
TNK2 tyrosine kinase, non-receptor, 2
TNP2 transition protein 2 (during histone to protamine replacement)
TNS2 tensin 2
TSC22D3 TSC22 domain family, member 3
VSIG4 V-set and immunoglobulin domain containing 4
WDR59 WD repeat domain 59
ZNF415 zinc finger protein 415

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARMC7 armadillo repeat containing 7
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BEND5 BEN domain containing 5
BIK BCL2-interacting killer (apoptosis-inducing)
BRAF B-Raf proto-oncogene, serine/threonine kinase
C16ORF59 chromosome 16 open reading frame 59
CCL2 chemokine (C-C motif) ligand 2
CD320 CD320 molecule
CENPT centromere protein T
CFAP69 cilia and flagella associated protein 69
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIDEC cell death-inducing DFFA-like effector c
CLDN15 claudin 15
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRELD1 cysteine-rich with EGF-like domains 1
CROT carnitine O-octanoyltransferase
CRYL1 crystallin, lambda 1
CTIF CBP80/20-dependent translation initiation factor
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM3 dynamin 3
DUSP8 dual specificity phosphatase 8
DVL1 dishevelled segment polarity protein 1
FAM127B family with sequence similarity 127, member B
FAM135A family with sequence similarity 135, member A
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FOXO4 forkhead box O4
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GPR132 G protein-coupled receptor 132
HAMP hepcidin antimicrobial peptide
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGLV1-44 immunoglobulin lambda variable 1-44
INO80D INO80 complex subunit D
IRX5 iroquois homeobox 5
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0753 KIAA0753
KIAA1024 KIAA1024
KLF3 Kruppel-like factor 3 (basic)
KLK5 kallikrein-related peptidase 5
L2HGDH L-2-hydroxyglutarate dehydrogenase
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00260 long intergenic non-protein coding RNA 260
LOC390998 ribosomal protein L10 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP3 low density lipoprotein receptor-related protein 3
LTC4S leukotriene C4 synthase
MANSC1 MANSC domain containing 1
MED31 mediator complex subunit 31
METTL2B methyltransferase like 2B
MSRA methionine sulfoxide reductase A
NIPAL2 NIPA-like domain containing 2
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPDC1 neural proliferation, differentiation and control, 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDGFD platelet derived growth factor D
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMFBP1 polyamine modulated factor 1 binding protein 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
QSER1 glutamine and serine rich 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF122 ring finger protein 122
SH2B2 SH2B adaptor protein 2
SIL1 SIL1 nucleotide exchange factor
SIRAL2 SIR2 antiphage like 2
SLC12A8 solute carrier family 12, member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLPI secretory leukocyte peptidase inhibitor
SP140 SP140 nuclear body protein
SPHK1 sphingosine kinase 1
SPON2 spondin 2, extracellular matrix protein
STBD1 starch binding domain 1
STK25 serine/threonine kinase 25
STX11 syntaxin 11
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I
TEX264 testis expressed 264
THEM6 thioesterase superfamily member 6
TMEM212 transmembrane protein 212
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPM3 tropomyosin 3
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSC22D4 TSC22 domain family, member 4
TUFT1 tuftelin 1
UNC13B unc-13 homolog B (C. elegans)
USP32 ubiquitin specific peptidase 32
ZMYM3 zinc finger, MYM-type 3
ZNF280B zinc finger protein 280B
ZNF41 zinc finger protein 41
ZNF667 zinc finger protein 667
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2