rolipram-5330 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the rolipram-5330 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB2 adhesion G protein-coupled receptor B2
AHNAK2 AHNAK nucleoprotein 2
ALS2CL ALS2 C-terminal like
APC adenomatous polyposis coli
APOL2 apolipoprotein L, 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASPH aspartate beta-hydroxylase
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C19ORF73 chromosome 19 open reading frame 73
C1QTNF3 C1q and tumor necrosis factor related protein 3
CACTIN cactin, spliceosome C complex subunit
CCNO cyclin O
CDKL3 cyclin-dependent kinase-like 3
CPTP ceramide-1-phosphate transfer protein
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DSCAM Down syndrome cell adhesion molecule
ELK1 ELK1, member of ETS oncogene family
EML2 echinoderm microtubule associated protein like 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
FADS3 fatty acid desaturase 3
FBXL2 F-box and leucine-rich repeat protein 2
FGF6 fibroblast growth factor 6
FRMPD1 FERM and PDZ domain containing 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GRM8 glutamate receptor, metabotropic 8
HFE hemochromatosis
IDI2-AS1 IDI2 antisense RNA 1
IFNA17 interferon, alpha 17
INO80D INO80 complex subunit D
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITSN1 intersectin 1 (SH3 domain protein)
JAKMIP2 janus kinase and microtubule interacting protein 2
KCTD13 potassium channel tetramerization domain containing 13
KDM4B lysine (K)-specific demethylase 4B
KLHL25 kelch-like family member 25
LIF leukemia inhibitory factor
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAP1B microtubule-associated protein 1B
MAP2K7 mitogen-activated protein kinase kinase 7
MED16 mediator complex subunit 16
MERTK MER proto-oncogene, tyrosine kinase
MICALL1 MICAL-like 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MIR622 microRNA 622
MTERF4 mitochondrial transcription termination factor 4
NLRX1 NLR family member X1
NNAT neuronatin
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
OSMR oncostatin M receptor
PCNX pecanex homolog (Drosophila)
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIAS1 protein inhibitor of activated STAT, 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PTN pleiotrophin
RAB36 RAB36, member RAS oncogene family
RAD54B RAD54 homolog B (S. cerevisiae)
RGS10 regulator of G-protein signaling 10
RUNX1 runt-related transcription factor 1
SERHL2 serine hydrolase-like 2
SFXN3 sideroflexin 3
SIVA1 SIVA1, apoptosis-inducing factor
SKIL SKI-like proto-oncogene
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13
SLMO1 slowmo homolog 1 (Drosophila)
SOCS2 suppressor of cytokine signaling 2
SPPL2B signal peptide peptidase like 2B
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRCAP Snf2-related CREBBP activator protein
STARD8 StAR-related lipid transfer (START) domain containing 8
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAZ tafazzin
TBC1D17 TBC1 domain family, member 17
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM104 transmembrane protein 104
TMEM180 transmembrane protein 180
TMEM80 transmembrane protein 80
TPST2 tyrosylprotein sulfotransferase 2
TRIM29 tripartite motif containing 29
TTC23 tetratricopeptide repeat domain 23
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VN1R1 vomeronasal 1 receptor 1
WNT6 wingless-type MMTV integration site family, member 6
YIPF2 Yip1 domain family, member 2
ZBTB17 zinc finger and BTB domain containing 17
ZBTB25 zinc finger and BTB domain containing 25
ZIC3 Zic family member 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF224 zinc finger protein 224
ZNF287 zinc finger protein 287
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGO1 argonaute RISC catalytic component 1
AIDA axin interactor, dorsalization associated
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKRD40 ankyrin repeat domain 40
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANXA2P3 annexin A2 pseudogene 3
ASNSD1 asparagine synthetase domain containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEX4 brain expressed, X-linked 4
BIK BCL2-interacting killer (apoptosis-inducing)
BLMH bleomycin hydrolase
C17ORF75 chromosome 17 open reading frame 75
C1ORF159 chromosome 1 open reading frame 159
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMKMT calmodulin-lysine N-methyltransferase
CARD8 caspase recruitment domain family, member 8
CBX4 chromobox homolog 4
CCDC47 coiled-coil domain containing 47
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCAF6 DDB1 and CUL4 associated factor 6
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EFHC1 EF-hand domain (C-terminal) containing 1
EFHD2 EF-hand domain family, member D2
ETAA1 Ewing tumor-associated antigen 1
FAM13B family with sequence similarity 13, member B
FBXL15 F-box and leucine-rich repeat protein 15
FLRT3 fibronectin leucine rich transmembrane protein 3
FNBP1L formin binding protein 1-like
FPGS folylpolyglutamate synthase
H1FX H1 histone family, member X
HIRA histone cell cycle regulator
HIST2H2AA3 histone cluster 2, H2aa3
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IREB2 iron-responsive element binding protein 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLF11 Kruppel-like factor 11
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LYPD1 LY6/PLAUR domain containing 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MKNK2 MAP kinase interacting serine/threonine kinase 2
MT1H metallothionein 1H
MUM1 melanoma associated antigen (mutated) 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NOL6 nucleolar protein 6 (RNA-associated)
NOTCH1 notch 1
NPM3 nucleophosmin/nucleoplasmin 3
NR1H2 nuclear receptor subfamily 1, group H, member 2
NT5C 5', 3'-nucleotidase, cytosolic
PDZRN3 PDZ domain containing ring finger 3
PLA2G12A phospholipase A2, group XIIA
PPAP2C phosphatidic acid phosphatase type 2C
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PROS1 protein S (alpha)
PSKH1 protein serine kinase H1
PYCRL pyrroline-5-carboxylate reductase-like
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TESK1 testis-specific kinase 1
TMEM165 transmembrane protein 165
TMEM2 transmembrane protein 2
TMEM39A transmembrane protein 39A
TMOD3 tropomodulin 3 (ubiquitous)
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRAF5 TNF receptor-associated factor 5
TRIM66 tripartite motif containing 66
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC1 tuberous sclerosis 1
TTC31 tetratricopeptide repeat domain 31
TTF2 transcription termination factor, RNA polymerase II
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP69B ZFP69 zinc finger protein B
ZNF184 zinc finger protein 184
ZNF189 zinc finger protein 189
ZNF571 zinc finger protein 571
ZNF7 zinc finger protein 7
ZNF768 zinc finger protein 768
ZNF787 zinc finger protein 787