rolipram-6730 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the rolipram-6730 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AFF2 AF4/FMR2 family, member 2
ANGPTL2 angiopoietin-like 2
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ATF6B activating transcription factor 6 beta
ATF7IP activating transcription factor 7 interacting protein
BAGE B melanoma antigen
BBC3 BCL2 binding component 3
BMP8B bone morphogenetic protein 8b
C10ORF12 chromosome 10 open reading frame 12
C9ORF9 chromosome 9 open reading frame 9
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC71 coiled-coil domain containing 71
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CDK13 cyclin-dependent kinase 13
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLCA2 chloride channel accessory 2
CLSTN3 calsyntenin 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
DCC DCC netrin 1 receptor
DMBT1 deleted in malignant brain tumors 1
DST dystonin
DUSP1 dual specificity phosphatase 1
EFR3B EFR3 homolog B (S. cerevisiae)
ELOVL5 ELOVL fatty acid elongase 5
EPB41L1 erythrocyte membrane protein band 4.1-like 1
FKRP fukutin related protein
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GOLGA8A golgin A8 family, member A
HLF hepatic leukemia factor
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGHA1 immunoglobulin heavy constant alpha 1
IGLJ3 immunoglobulin lambda joining 3
IL11 interleukin 11
ISG20 interferon stimulated exonuclease gene 20kDa
KIAA0485 uncharacterized LOC57235
KRT86 keratin 86, type II
LEFTY2 left-right determination factor 2
LIPG lipase, endothelial
LMOD1 leiomodin 1 (smooth muscle)
LRP4 low density lipoprotein receptor-related protein 4
LTBP4 latent transforming growth factor beta binding protein 4
MCC mutated in colorectal cancers
MCTP2 multiple C2 domains, transmembrane 2
MFAP3L microfibrillar-associated protein 3-like
MPPE1 metallophosphoesterase 1
MRPS12 mitochondrial ribosomal protein S12
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MTMR3 myotubularin related protein 3
MX1 MX dynamin-like GTPase 1
NPR2 natriuretic peptide receptor 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PARVA parvin, alpha
PCDH17 protocadherin 17
PLXNC1 plexin C1
POU2F2 POU class 2 homeobox 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRDM10 PR domain containing 10
PTGDR2 prostaglandin D2 receptor 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAI2 retinoic acid induced 2
RB1 retinoblastoma 1
RBFA ribosome binding factor A (putative)
RIN3 Ras and Rab interactor 3
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SFRP4 secreted frizzled-related protein 4
SLAMF7 SLAM family member 7
SPAG11A sperm associated antigen 11A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STC1 stanniocalcin 1
STX7 syntaxin 7
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TENM1 teneurin transmembrane protein 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFEB transcription factor EB
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TPM3 tropomyosin 3
TSGA10 testis specific, 10
TTLL1 tubulin tyrosine ligase-like family member 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF518A zinc finger protein 518A
ZNF609 zinc finger protein 609
ZNF710 zinc finger protein 710
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
AFAP1 actin filament associated protein 1
APOL6 apolipoprotein L, 6
ARMC6 armadillo repeat containing 6
ASB8 ankyrin repeat and SOCS box containing 8
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
C1RL complement component 1, r subcomponent-like
C22ORF29 chromosome 22 open reading frame 29
C9ORF40 chromosome 9 open reading frame 40
CARTPT CART prepropeptide
CD79A CD79a molecule, immunoglobulin-associated alpha
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEC cell death-inducing DFFA-like effector c
CLDN1 claudin 1
CNN1 calponin 1, basic, smooth muscle
CPZ carboxypeptidase Z
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAL4 dynein, axonemal, light chain 4
EPHA7 EPH receptor A7
FAM188A family with sequence similarity 188, member A
FAT4 FAT atypical cadherin 4
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLT4 fms-related tyrosine kinase 4
GATA4 GATA binding protein 4
GIF gastric intrinsic factor (vitamin B synthesis)
GRAMD1C GRAM domain containing 1C
GREB1L growth regulation by estrogen in breast cancer-like
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
HIST1H3A histone cluster 1, H3a
HOOK1 hook microtubule-tethering protein 1
HOXA7 homeobox A7
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IFT54 intraflagellar transport 54
IL36RN interleukin 36 receptor antagonist
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0355 KIAA0355
KPTN kaptin (actin binding protein)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7B lin-7 homolog B (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
LRRK1 leucine-rich repeat kinase 1
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K7CL MAP3K7 C-terminal like
MMP13 matrix metallopeptidase 13
NEUROD1 neuronal differentiation 1
NINJ1 ninjurin 1
NPFFR1 neuropeptide FF receptor 1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSR2 odd-skipped related transciption factor 2
OVGP1 oviductal glycoprotein 1, 120kDa
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PACS1 phosphofurin acidic cluster sorting protein 1
PID1 phosphotyrosine interaction domain containing 1
PKD2L2 polycystic kidney disease 2-like 2
PLAG1 pleiomorphic adenoma gene 1
PLCD1 phospholipase C, delta 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRAMEF10 PRAME family member 10
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RIN1 Ras and Rab interactor 1
RPGRIP1L RPGRIP1-like
SALL2 spalt-like transcription factor 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD6 SET domain containing 6
SLC16A6 solute carrier family 16, member 6
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBXAS1 thromboxane A synthase 1 (platelet)
TESK1 testis-specific kinase 1
TLR2 toll-like receptor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM53 transmembrane protein 53
TRPV1 transient receptor potential cation channel, subfamily V, member 1
WNT1 wingless-type MMTV integration site family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
ZNF10 zinc finger protein 10
ZNF84 zinc finger protein 84
ZNF862 zinc finger protein 862
ZNHIT2 zinc finger, HIT-type containing 2