| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the rolitetracycline-3031 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALX1 | ALX homeobox 1 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| AREG | amphiregulin |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAIAP2 | BAI1-associated protein 2 |
| BMP7 | bone morphogenetic protein 7 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CALD1 | caldesmon 1 |
| CASR | calcium-sensing receptor |
| CCDC170 | coiled-coil domain containing 170 |
| CCDC9 | coiled-coil domain containing 9 |
| CD180 | CD180 molecule |
| CD22 | CD22 molecule |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCA1 | chloride channel accessory 1 |
| CLDN9 | claudin 9 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CRB1 | crumbs family member 1, photoreceptor morphogenesis associated |
| CYHR1 | cysteine/histidine-rich 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| EGFR | epidermal growth factor receptor |
| EGR4 | early growth response 4 |
| FCAR | Fc fragment of IgA receptor |
| FGFR2 | fibroblast growth factor receptor 2 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FN1 | fibronectin 1 |
| FOXF1 | forkhead box F1 |
| FRMPD4 | FERM and PDZ domain containing 4 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GATA6 | GATA binding protein 6 |
| GK3P | glycerol kinase 3 pseudogene |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPATCH4 | G patch domain containing 4 |
| GPR35 | G protein-coupled receptor 35 |
| GRIA4 | glutamate receptor, ionotropic, AMPA 4 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HAB1 | B1 for mucin |
| HFE | hemochromatosis |
| HIST1H2BC | histone cluster 1, H2bc |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HOXD3 | homeobox D3 |
| HR | hair growth associated |
| IDS | iduronate 2-sulfatase |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KCNIP2 | Kv channel interacting protein 2 |
| KCNJ9 | potassium channel, inwardly rectifying subfamily J, member 9 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDSR | 3-ketodihydrosphingosine reductase |
| KLK7 | kallikrein-related peptidase 7 |
| LBX1 | ladybird homeobox 1 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHX6 | LIM homeobox 6 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NPY | neuropeptide Y |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NRAP | nebulin-related anchoring protein |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PDE10A | phosphodiesterase 10A |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PTTG2 | pituitary tumor-transforming 2 |
| PVR | poliovirus receptor |
| RAB40C | RAB40C, member RAS oncogene family |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFRP5 | secreted frizzled-related protein 5 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPARCL1 | SPARC-like 1 (hevin) |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TFR2 | transferrin receptor 2 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TUBA4B | tubulin, alpha 4b |
| ZBTB7B | zinc finger and BTB domain containing 7B |
| ZNF556 | zinc finger protein 556 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATG9A | autophagy related 9A |
| BSPRY | B-box and SPRY domain containing |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAPN5 | calpain 5 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC69 | coiled-coil domain containing 69 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDON | cell adhesion associated, oncogene regulated |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP1A | charged multivesicular body protein 1A |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CROT | carnitine O-octanoyltransferase |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOLK | dolichol kinase |
| DPYS | dihydropyrimidinase |
| DYM | dymeclin |
| FAM127A | family with sequence similarity 127, member A |
| FAM204A | family with sequence similarity 204, member A |
| FAM57A | family with sequence similarity 57, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FER | fer (fps/fes related) tyrosine kinase |
| FKBPL | FK506 binding protein like |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GID4 | GID complex subunit 4 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3G | histone cluster 1, H3g |
| IBSP | integrin-binding sialoprotein |
| ICK | intestinal cell (MAK-like) kinase |
| INCENP | inner centromere protein antigens 135/155kDa |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MICA | MHC class I polypeptide-related sequence A |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NCKAP1L | NCK-associated protein 1-like |
| NCS1 | neuronal calcium sensor 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PEPD | peptidase D |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G15 | phospholipase A2, group XV |
| PNMA1 | paraneoplastic Ma antigen 1 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PROCR | protein C receptor, endothelial |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SIX3 | SIX homeobox 3 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| TAGLN | transgelin |
| TBKBP1 | TBK1 binding protein 1 |
| TLR6 | toll-like receptor 6 |
| TMEM110 | transmembrane protein 110 |
| TMEM120B | transmembrane protein 120B |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TOLLIP | toll interacting protein |
| TRIM25 | tripartite motif containing 25 |
| UNC13B | unc-13 homolog B (C. elegans) |
| USP32 | ubiquitin specific peptidase 32 |
| XYLT2 | xylosyltransferase II |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF248 | zinc finger protein 248 |
| ZNF506 | zinc finger protein 506 |
| ZNF76 | zinc finger protein 76 |
