| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the rolitetracycline-3369 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACTN2 | actinin, alpha 2 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADCY2 | adenylate cyclase 2 (brain) |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C7 | complement component 7 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CCDC40 | coiled-coil domain containing 40 |
| CCDC64 | coiled-coil domain containing 64 |
| CD47 | CD47 molecule |
| CD6 | CD6 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CEP41 | centrosomal protein 41kDa |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DIO2 | deiodinase, iodothyronine, type II |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| DOCK3 | dedicator of cytokinesis 3 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DOK4 | docking protein 4 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EGF | epidermal growth factor |
| ERCC2 | excision repair cross-complementation group 2 |
| FGA | fibrinogen alpha chain |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FSTL1 | follistatin-like 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GRB10 | growth factor receptor-bound protein 10 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IL1RN | interleukin 1 receptor antagonist |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MON2 | MON2 homolog (S. cerevisiae) |
| MST1 | macrophage stimulating 1 |
| MYOF | myoferlin |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDRG2 | NDRG family member 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PTAFR | platelet-activating factor receptor |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RHAG | Rh-associated glycoprotein |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| S100A7 | S100 calcium binding protein A7 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SIK2 | salt-inducible kinase 2 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC35E2 | solute carrier family 35, member E2 |
| SPAG8 | sperm associated antigen 8 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPRR3 | small proline-rich protein 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| T | T, brachyury homolog (mouse) |
| TBXA2R | thromboxane A2 receptor |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TTC39A | tetratricopeptide repeat domain 39A |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP46 | ubiquitin specific peptidase 46 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AHR | aryl hydrocarbon receptor |
| AIM1 | absent in melanoma 1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNK | cyclin K |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CES3 | carboxylesterase 3 |
| CHKB | choline kinase beta |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DEAF1 | DEAF1 transcription factor |
| DSC2 | desmocollin 2 |
| DYSF | dysferlin |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXOC5 | exocyst complex component 5 |
| FKBP5 | FK506 binding protein 5 |
| FOXI1 | forkhead box I1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L | galactosidase, beta 1-like |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR143 | G protein-coupled receptor 143 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H4A | histone cluster 1, H4a |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0319L | KIAA0319-like |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MBTD1 | mbt domain containing 1 |
| MED18 | mediator complex subunit 18 |
| MITF | microphthalmia-associated transcription factor |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOL10 | nucleolar protein 10 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSMR | oncostatin M receptor |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDHA6 | protocadherin alpha 6 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PRAMEF11 | PRAME family member 11 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| SECTM1 | secreted and transmembrane 1 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPRYD7 | SPRY domain containing 7 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBCCD1 | TBCC domain containing 1 |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMEM242 | transmembrane protein 242 |
| TMEM254 | transmembrane protein 254 |
| TRIM16 | tripartite motif containing 16 |
| TWISTNB | TWIST neighbor |
| UPP1 | uridine phosphorylase 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR76 | WD repeat domain 76 |
| WDR78 | WD repeat domain 78 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF286A | zinc finger protein 286A |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF862 | zinc finger protein 862 |
