| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the rolitetracycline-6731 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ACVR1B | activin A receptor, type IB |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADRB3 | adrenoceptor beta 3 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATF6B | activating transcription factor 6 beta |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B9D2 | B9 protein domain 2 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP8B | bone morphogenetic protein 8b |
| CD163 | CD163 molecule |
| COL10A1 | collagen, type X, alpha 1 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CTRL | chymotrypsin-like |
| CTSS | cathepsin S |
| CXORF21 | chromosome X open reading frame 21 |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DMPK | dystrophia myotonica-protein kinase |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ETV6 | ets variant 6 |
| EXO5 | exonuclease 5 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FBXO41 | F-box protein 41 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPX3 | glutathione peroxidase 3 |
| HDAC6 | histone deacetylase 6 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXD1 | homeobox D1 |
| HRG | histidine-rich glycoprotein |
| IL11 | interleukin 11 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KDM5B | lysine (K)-specific demethylase 5B |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMB4 | laminin, beta 4 |
| LOXL3 | lysyl oxidase-like 3 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MST1 | macrophage stimulating 1 |
| NME5 | NME/NM23 family member 5 |
| NNMT | nicotinamide N-methyltransferase |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL10 | nucleolar protein 10 |
| PAPOLG | poly(A) polymerase gamma |
| PASK | PAS domain containing serine/threonine kinase |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEK | pleckstrin |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| POU4F1 | POU class 4 homeobox 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKCE | protein kinase C, epsilon |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAP2B | RAP2B, member of RAS oncogene family |
| REN | renin |
| RHOT2 | ras homolog family member T2 |
| RIN3 | Ras and Rab interactor 3 |
| RPS3A | ribosomal protein S3A |
| RRAGD | Ras-related GTP binding D |
| S100A13 | S100 calcium binding protein A13 |
| SCARB1 | scavenger receptor class B, member 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLAMF7 | SLAM family member 7 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SOCS3 | suppressor of cytokine signaling 3 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TBC1D4 | TBC1 domain family, member 4 |
| TFR2 | transferrin receptor 2 |
| TGFB1 | transforming growth factor, beta 1 |
| TNS1 | tensin 1 |
| TOP3B | topoisomerase (DNA) III beta |
| TPM3 | tropomyosin 3 |
| TROVE2 | TROVE domain family, member 2 |
| UPK1B | uroplakin 1B |
| USP22 | ubiquitin specific peptidase 22 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZNF155 | zinc finger protein 155 |
| ZNF268 | zinc finger protein 268 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| APOC4 | apolipoprotein C-IV |
| APOL6 | apolipoprotein L, 6 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARTPT | CART prepropeptide |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDHR2 | cadherin-related family member 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLDN1 | claudin 1 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CPNE7 | copine VII |
| CPZ | carboxypeptidase Z |
| DNM3 | dynamin 3 |
| DSPP | dentin sialophosphoprotein |
| DUSP8 | dual specificity phosphatase 8 |
| EFNA3 | ephrin-A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FGF23 | fibroblast growth factor 23 |
| FGL1 | fibrinogen-like 1 |
| FLCN | folliculin |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMD8 | FERM domain containing 8 |
| GATA4 | GATA binding protein 4 |
| GMPR | guanosine monophosphate reductase |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H2BO | histone cluster 1, H2bo |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC8 | homeobox C8 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| IL6 | interleukin 6 |
| JMJD4 | jumonji domain containing 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KRT31 | keratin 31, type I |
| LOC257152 | uncharacterized LOC257152 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MTSS1L | metastasis suppressor 1-like |
| NAG18 | NAG18 mRNA |
| NEK11 | NIMA-related kinase 11 |
| NEUROD1 | neuronal differentiation 1 |
| NOL12 | nucleolar protein 12 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OSBP2 | oxysterol binding protein 2 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCBP4 | poly(rC) binding protein 4 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PRAMEF10 | PRAME family member 10 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RAPSN | receptor-associated protein of the synapse |
| RGCC | regulator of cell cycle |
| RGS17 | regulator of G-protein signaling 17 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCG2 | secretogranin II |
| SCIN | scinderin |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STEAP4 | STEAP family member 4 |
| TBC1D22B | TBC1 domain family, member 22B |
| TNS2 | tensin 2 |
| TOLLIP | toll interacting protein |
| TRABD | TraB domain containing |
| TUBG2 | tubulin, gamma 2 |
| YY2 | YY2 transcription factor |
| ZNF350 | zinc finger protein 350 |
| ZNF446 | zinc finger protein 446 |
| ZNF510 | zinc finger protein 510 |
| ZNF816 | zinc finger protein 816 |
