ronidazole-7131 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ronidazole-7131 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AMDHD2 amidohydrolase domain containing 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
CA9 carbonic anhydrase IX
CACYBP calcyclin binding protein
CD22 CD22 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
COL5A1 collagen, type V, alpha 1
COPS8 COP9 signalosome subunit 8
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTSF cathepsin F
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
EFNA5 ephrin-A5
ETV1 ets variant 1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKBP8 FK506 binding protein 8, 38kDa
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK glycerol kinase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA8A golgin A8 family, member A
GRK6 G protein-coupled receptor kinase 6
HCRP1 hepatocellular carcinoma-related HCRP1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA4 homeobox A4
HSDL2 hydroxysteroid dehydrogenase like 2
HSF2 heat shock transcription factor 2
IDS iduronate 2-sulfatase
IL11RA interleukin 11 receptor, alpha
IL33 interleukin 33
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
KDM4C lysine (K)-specific demethylase 4C
KIF5C kinesin family member 5C
KLF2 Kruppel-like factor 2
KRT34 keratin 34, type I
LIMK1 LIM domain kinase 1
LMF2 lipase maturation factor 2
LOC81691 exonuclease NEF-sp
LTBP2 latent transforming growth factor beta binding protein 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MAPK12 mitogen-activated protein kinase 12
MAPK7 mitogen-activated protein kinase 7
MAPT microtubule-associated protein tau
MFSD11 major facilitator superfamily domain containing 11
MTA1 metastasis associated 1
MUC4 mucin 4, cell surface associated
MXRA8 matrix-remodelling associated 8
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NF2 neurofibromin 2 (merlin)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NT5DC3 5'-nucleotidase domain containing 3
NUMA1 nuclear mitotic apparatus protein 1
PAX9 paired box 9
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PEX26 peroxisomal biogenesis factor 26
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PVT1 Pvt1 oncogene (non-protein coding)
RAB31 RAB31, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RASAL2 RAS protein activator like 2
RBKS ribokinase
RPLP2 ribosomal protein, large, P2
RTN2 reticulon 2
SCAPER S-phase cyclin A-associated protein in the ER
SCG2 secretogranin II
SERGEF secretion regulating guanine nucleotide exchange factor
SIRT3 sirtuin 3
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC6A16 solute carrier family 6, member 16
SMO smoothened, frizzled class receptor
SMYD2 SET and MYND domain containing 2
SREBF2 sterol regulatory element binding transcription factor 2
SRPX2 sushi-repeat containing protein, X-linked 2
STK4 serine/threonine kinase 4
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TESK2 testis-specific kinase 2
THOC5 THO complex 5
TTC38 tetratricopeptide repeat domain 38
WHSC1 Wolf-Hirschhorn syndrome candidate 1
XYLB xylulokinase homolog (H. influenzae)
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFHX3 zinc finger homeobox 3
ZFPM2 zinc finger protein, FOG family member 2
ZFYVE9 zinc finger, FYVE domain containing 9

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABT1 activator of basal transcription 1
ADA adenosine deaminase
AKR1C3 aldo-keto reductase family 1, member C3
ASB6 ankyrin repeat and SOCS box containing 6
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BPHL biphenyl hydrolase-like (serine hydrolase)
CCNE1 cyclin E1
CCNT1 cyclin T1
CFAP44 cilia and flagella associated protein 44
CFD complement factor D (adipsin)
CIR1 corepressor interacting with RBPJ, 1
CRIP2 cysteine-rich protein 2
DDB1 damage-specific DNA binding protein 1, 127kDa
DENND5B DENN/MADD domain containing 5B
DNAAF2 dynein, axonemal, assembly factor 2
ERCC2 excision repair cross-complementation group 2
FAM102A family with sequence similarity 102, member A
FAM188A family with sequence similarity 188, member A
FAM86C1 family with sequence similarity 86, member C1
FBXO46 F-box protein 46
GID4 GID complex subunit 4
GPR176 G protein-coupled receptor 176
GRWD1 glutamate-rich WD repeat containing 1
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
HYAL3 hyaluronoglucosaminidase 3
INCENP inner centromere protein antigens 135/155kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPO8 importin 8
LZTR1 leucine-zipper-like transcription regulator 1
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCRS1 microspherule protein 1
MCTP1 multiple C2 domains, transmembrane 1
METRN meteorin, glial cell differentiation regulator
MFSD12 major facilitator superfamily domain containing 12
MNT MAX network transcriptional repressor
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUS81 MUS81 structure-specific endonuclease subunit
MYL5 myosin, light chain 5, regulatory
NABP2 nucleic acid binding protein 2
NINJ1 ninjurin 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLH polymerase (DNA directed), eta
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PROSER1 proline and serine rich 1
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RANBP17 RAN binding protein 17
RAP1GAP2 RAP1 GTPase activating protein 2
RARS arginyl-tRNA synthetase
RGS19 regulator of G-protein signaling 19
RHOB ras homolog family member B
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RRP1 ribosomal RNA processing 1
RUVBL1 RuvB-like AAA ATPase 1
S100P S100 calcium binding protein P
SDAD1 SDA1 domain containing 1
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SF3A3 splicing factor 3a, subunit 3, 60kDa
SIX1 SIX homeobox 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC41A3 solute carrier family 41, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK25 serine/threonine kinase 25
SYTL2 synaptotagmin-like 2
THAP10 THAP domain containing 10
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TMC5 transmembrane channel-like 5
TMEM242 transmembrane protein 242
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBTD1 ubiquitin domain containing 1
USP6NL USP6 N-terminal like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
ZDHHC11 zinc finger, DHHC-type containing 11
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF350 zinc finger protein 350
ZNF385D zinc finger protein 385D
ZSCAN26 zinc finger and SCAN domain containing 26
ZXDC ZXD family zinc finger C