rora Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description RAR-related orphan receptor A|The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 6095)
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Genes

8 genes co-occuring with the biological term rora in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CLOCK clock circadian regulator
MTNR1B melatonin receptor 1B
NPAS2 neuronal PAS domain protein 2
NPSR1 neuropeptide S receptor 1
NR1D1 nuclear receptor subfamily 1, group D, member 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RORA RAR-related orphan receptor A
TIMELESS timeless circadian clock