rosiglitazone-1658 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the rosiglitazone-1658 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AHNAK2 AHNAK nucleoprotein 2
AK2 adenylate kinase 2
ALS2CL ALS2 C-terminal like
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARL3 ADP-ribosylation factor-like 3
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP activating transcription factor 7 interacting protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C18ORF25 chromosome 18 open reading frame 25
C21ORF2 chromosome 21 open reading frame 2
CACTIN cactin, spliceosome C complex subunit
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASKIN2 CASK interacting protein 2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK3 cyclin-dependent kinase 3
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CHKB choline kinase beta
CIITA class II, major histocompatibility complex, transactivator
CNOT8 CCR4-NOT transcription complex, subunit 8
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CORT cortistatin
CREBZF CREB/ATF bZIP transcription factor
CRELD1 cysteine-rich with EGF-like domains 1
CTAGE5 CTAGE family, member 5
CTSD cathepsin D
CYHR1 cysteine/histidine-rich 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ELK1 ELK1, member of ETS oncogene family
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ESR1 estrogen receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM174B family with sequence similarity 174, member B
FAS Fas cell surface death receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FH fumarate hydratase
FN1 fibronectin 1
FSCN1 fascin actin-bundling protein 1
GEMIN4 gem (nuclear organelle) associated protein 4
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLA-G major histocompatibility complex, class I, G
HOMER3 homer scaffolding protein 3
HSPB11 heat shock protein family B (small), member 11
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIF13B kinesin family member 13B
LAMP1 lysosomal-associated membrane protein 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MEIS2 Meis homeobox 2
METTL3 methyltransferase like 3
METTL5 methyltransferase like 5
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NCAPH2 non-SMC condensin II complex, subunit H2
NDRG2 NDRG family member 2
NEB nebulin
OLFM1 olfactomedin 1
OSMR oncostatin M receptor
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLAUR plasminogen activator, urokinase receptor
POMT2 protein-O-mannosyltransferase 2
PPAP2B phosphatidic acid phosphatase type 2B
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTGES prostaglandin E synthase
RARA retinoic acid receptor, alpha
RNF43 ring finger protein 43
RS1 retinoschisin 1
RTEL1 regulator of telomere elongation helicase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH2B1 SH2B adaptor protein 1
SHARPIN SHANK-associated RH domain interactor
SIPA1L3 signal-induced proliferation-associated 1 like 3
SMAD3 SMAD family member 3
SMTN smoothelin
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
TGM2 transglutaminase 2
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLN2 talin 2
TMOD1 tropomodulin 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TUBA3C tubulin, alpha 3c
VAC14 Vac14 homolog (S. cerevisiae)
VGF VGF nerve growth factor inducible
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPF1 WAS/WASL interacting protein family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
ZFYVE9 zinc finger, FYVE domain containing 9
ZHX3 zinc fingers and homeoboxes 3
ZNF227 zinc finger protein 227
ZNF500 zinc finger protein 500
ZNF606 zinc finger protein 606
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOD apolipoprotein D
ARMC6 armadillo repeat containing 6
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L2 BCL2-like 2
C9ORF91 chromosome 9 open reading frame 91
CDK5 cyclin-dependent kinase 5
CDKL3 cyclin-dependent kinase-like 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIDEC cell death-inducing DFFA-like effector c
CLCF1 cardiotrophin-like cytokine factor 1
CLCN2 chloride channel, voltage-sensitive 2
CLK1 CDC-like kinase 1
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CUEDC1 CUE domain containing 1
DAAM1 dishevelled associated activator of morphogenesis 1
DCP1A decapping mRNA 1A
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
ENY2 enhancer of yellow 2 homolog (Drosophila)
F8 coagulation factor VIII, procoagulant component
FAM50B family with sequence similarity 50, member B
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GBP2 guanylate binding protein 2, interferon-inducible
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTPBP2 GTP binding protein 2
IRAK4 interleukin-1 receptor-associated kinase 4
IRF7 interferon regulatory factor 7
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
KIAA0513 KIAA0513
KIAA0922 KIAA0922
LNPEP leucyl/cystinyl aminopeptidase
LOC257152 uncharacterized LOC257152
MAP9 microtubule-associated protein 9
METTL16 methyltransferase like 16
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTMR12 myotubularin related protein 12
NFE2L3 nuclear factor, erythroid 2-like 3
NMU neuromedin U
NPFFR1 neuropeptide FF receptor 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
OGFRL1 opioid growth factor receptor-like 1
PBLD phenazine biosynthesis-like protein domain containing
PCTP phosphatidylcholine transfer protein
PEX26 peroxisomal biogenesis factor 26
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PMCH pro-melanin-concentrating hormone
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
RANBP17 RAN binding protein 17
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
RIPK4 receptor-interacting serine-threonine kinase 4
S100A4 S100 calcium binding protein A4
SETD8 SET domain containing (lysine methyltransferase) 8
SFT2D2 SFT2 domain containing 2
SIRAL2 SIR2 antiphage like 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A4RG SLC2A4 regulator
SLC35E3 solute carrier family 35, member E3
SLC35F6 solute carrier family 35, member F6
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMA4 glucuronidase, beta pseudogene
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNORA21 small nucleolar RNA, H/ACA box 21
SOBP sine oculis binding protein homolog (Drosophila)
SOX12 SRY (sex determining region Y)-box 12
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TACC3 transforming, acidic coiled-coil containing protein 3
TBCC tubulin folding cofactor C
THAP7 THAP domain containing 7
TMEM180 transmembrane protein 180
TMEM254 transmembrane protein 254
TPTE transmembrane phosphatase with tensin homology
TSPYL2 TSPY-like 2
UBXN8 UBX domain protein 8
VEGFC vascular endothelial growth factor C
WRN Werner syndrome, RecQ helicase-like
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF254 zinc finger protein 254
ZNF324 zinc finger protein 324
ZNF331 zinc finger protein 331
ZNF516 zinc finger protein 516
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZNF85 zinc finger protein 85
ZNHIT2 zinc finger, HIT-type containing 2