rosiglitazone-369 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the rosiglitazone-369 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ACRV1 acrosomal vesicle protein 1
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANP32A-IT1 ANP32A intronic transcript 1
ARHGAP33 Rho GTPase activating protein 33
ARMC4 armadillo repeat containing 4
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARRB2 arrestin, beta 2
AXIN1 axin 1
C20ORF27 chromosome 20 open reading frame 27
CA5B carbonic anhydrase VB, mitochondrial
CALHM2 calcium homeostasis modulator 2
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAV3 caveolin 3
CDC42 cell division cycle 42
CECR1 cat eye syndrome chromosome region, candidate 1
CEP72 centrosomal protein 72kDa
CFAP70 cilia and flagella associated protein 70
CLEC1B C-type lectin domain family 1, member B
CLEC2B C-type lectin domain family 2, member B
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYB561 cytochrome b561
CYLD cylindromatosis (turban tumor syndrome)
DHPS deoxyhypusine synthase
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
ELP6 elongator acetyltransferase complex subunit 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FH fumarate hydratase
FLNB filamin B, beta
G6PC3 glucose 6 phosphatase, catalytic, 3
GDF11 growth differentiation factor 11
GK glycerol kinase
GLRA2 glycine receptor, alpha 2
GM2A GM2 ganglioside activator
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA1 golgin A1
GP2 glycoprotein 2 (zymogen granule membrane)
GPR107 G protein-coupled receptor 107
GPR153 G protein-coupled receptor 153
GRK5 G protein-coupled receptor kinase 5
GTSE1 G-2 and S-phase expressed 1
GUSBP3 glucuronidase, beta pseudogene 3
HIPK2 homeodomain interacting protein kinase 2
HIST1H4J histone cluster 1, H4j
HMGN5 high mobility group nucleosome binding domain 5
HP1BP3 heterochromatin protein 1, binding protein 3
HPX hemopexin
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IRGQ immunity-related GTPase family, Q
JOSD1 Josephin domain containing 1
KDM2A lysine (K)-specific demethylase 2A
LOC729164 hCG1732469
LRRC37A3 leucine rich repeat containing 37, member A3
MAST2 microtubule associated serine/threonine kinase 2
MCF2L MCF.2 cell line derived transforming sequence-like
MGMT O-6-methylguanine-DNA methyltransferase
MST1 macrophage stimulating 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO1C myosin IC
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOP16 NOP16 nucleolar protein
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OMG oligodendrocyte myelin glycoprotein
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PEX10 peroxisomal biogenesis factor 10
PKN1 protein kinase N1
PLCD1 phospholipase C, delta 1
PNPLA6 patatin-like phospholipase domain containing 6
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
RAB3D RAB3D, member RAS oncogene family
RFWD3 ring finger and WD repeat domain 3
RRBP1 ribosome binding protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFTPC surfactant protein C
SGSH N-sulfoglucosamine sulfohydrolase
SIDT2 SID1 transmembrane family, member 2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SMG7 SMG7 nonsense mediated mRNA decay factor
SRRD SRR1 domain containing
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TESK2 testis-specific kinase 2
TGFA transforming growth factor, alpha
TRMT61A tRNA methyltransferase 61A
TUBA4B tubulin, alpha 4b
VGF VGF nerve growth factor inducible
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZMAT3 zinc finger, matrin-type 3
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACPP acid phosphatase, prostate
ACVR2B activin A receptor, type IIB
AQP8 aquaporin 8
ARHGAP11A Rho GTPase activating protein 11A
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CA6 carbonic anhydrase VI
CASZ1 castor zinc finger 1
CCDC177 coiled-coil domain containing 177
CD19 CD19 molecule
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHRM2 cholinergic receptor, muscarinic 2
CNTN1 contactin 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DSG2 desmoglein 2
ECE2 endothelin converting enzyme 2
ETV7 ets variant 7
FMOD fibromodulin
FUBP3 far upstream element (FUSE) binding protein 3
FYCO1 FYVE and coiled-coil domain containing 1
FZD4 frizzled class receptor 4
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GDF3 growth differentiation factor 3
GLB1L2 galactosidase, beta 1-like 2
HOOK2 hook microtubule-tethering protein 2
IGSF3 immunoglobulin superfamily, member 3
IL10 interleukin 10
JAM2 junctional adhesion molecule 2
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL3 kelch-like family member 3
KRT38 keratin 38, type I
LGALS14 lectin, galactoside-binding, soluble, 14
LINC00216 long intergenic non-protein coding RNA 216
LMAN2L lectin, mannose-binding 2-like
LONRF3 LON peptidase N-terminal domain and ring finger 3
LUZP4 leucine zipper protein 4
MAGEC2 melanoma antigen family C2
MAGOHB mago-nashi homolog B (Drosophila)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NGRN neugrin, neurite outgrowth associated
NNAT neuronatin
NRBP1 nuclear receptor binding protein 1
OPRK1 opioid receptor, kappa 1
PADI2 peptidyl arginine deiminase, type II
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PARD6A par-6 family cell polarity regulator alpha
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PCTP phosphatidylcholine transfer protein
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PITRM1 pitrilysin metallopeptidase 1
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLVAP plasmalemma vesicle associated protein
PRSS22 protease, serine, 22
RABL3 RAB, member of RAS oncogene family-like 3
RFPL2 ret finger protein-like 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIPK4 receptor-interacting serine-threonine kinase 4
RNF39 ring finger protein 39
RPUSD2 RNA pseudouridylate synthase domain containing 2
SATB1 SATB homeobox 1
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SIX6 SIX homeobox 6
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPDL1 spindle apparatus coiled-coil protein 1
TBR1 T-box, brain, 1
TGFB3 transforming growth factor, beta 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TIGAR TP53 induced glycolysis regulatory phosphatase
TINAGL1 tubulointerstitial nephritis antigen-like 1
TJP2 tight junction protein 2
TMEM184B transmembrane protein 184B
TMEM74B transmembrane protein 74B
TMPRSS5 transmembrane protease, serine 5
TPST1 tyrosylprotein sulfotransferase 1
TRAPPC12 trafficking protein particle complex 12
TRIM32 tripartite motif containing 32
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBB6 tubulin, beta 6 class V
UNC13B unc-13 homolog B (C. elegans)
USP29 ubiquitin specific peptidase 29
VPREB3 pre-B lymphocyte 3
WDR11 WD repeat domain 11
WNT16 wingless-type MMTV integration site family, member 16
ZNF232 zinc finger protein 232
ZNF35 zinc finger protein 35
ZNF480 zinc finger protein 480
ZNF557 zinc finger protein 557