| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the rosiglitazone-4457 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| ADM | adrenomedullin |
| AEN | apoptosis enhancing nuclease |
| ANGPTL2 | angiopoietin-like 2 |
| ANGPTL4 | angiopoietin-like 4 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATP10A | ATPase, class V, type 10A |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C2CD2L | C2CD2-like |
| CAT | catalase |
| CBLC | Cbl proto-oncogene C, E3 ubiquitin protein ligase |
| CD1A | CD1a molecule |
| CD209 | CD209 molecule |
| CDH7 | cadherin 7, type 2 |
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEP41 | centrosomal protein 41kDa |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FA2H | fatty acid 2-hydroxylase |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FYB | FYN binding protein |
| GPR85 | G protein-coupled receptor 85 |
| GRK4 | G protein-coupled receptor kinase 4 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IL1B | interleukin 1, beta |
| IRS2 | insulin receptor substrate 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JUN | jun proto-oncogene |
| KAZN | kazrin, periplakin interacting protein |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIRREL | kin of IRRE like (Drosophila) |
| KXD1 | KxDL motif containing 1 |
| LAMA4 | laminin, alpha 4 |
| LIPE | lipase, hormone-sensitive |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LPIN1 | lipin 1 |
| LTB4R | leukotriene B4 receptor |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MLN | motilin |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPY2R | neuropeptide Y receptor Y2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDLIM4 | PDZ and LIM domain 4 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLIN2 | perilipin 2 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKCD | protein kinase C, delta |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTGES | prostaglandin E synthase |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RHAG | Rh-associated glycoprotein |
| RHOB | ras homolog family member B |
| RHOF | ras homolog family member F (in filopodia) |
| RIN3 | Ras and Rab interactor 3 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SELPLG | selectin P ligand |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SORBS1 | sorbin and SH3 domain containing 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TGFB1 | transforming growth factor, beta 1 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TRA | T cell receptor alpha locus |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| VLDLR | very low density lipoprotein receptor |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AFF4 | AF4/FMR2 family, member 4 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BDNF | brain-derived neurotrophic factor |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BMP4 | bone morphogenetic protein 4 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CD70 | CD70 molecule |
| CES3 | carboxylesterase 3 |
| CLEC2B | C-type lectin domain family 2, member B |
| COL5A2 | collagen, type V, alpha 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTGF | connective tissue growth factor |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDN | dendrin |
| DENND3 | DENN/MADD domain containing 3 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO31 | F-box protein 31 |
| FZD8 | frizzled class receptor 8 |
| GAS8 | growth arrest-specific 8 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH2L | G patch domain containing 2-like |
| GRB7 | growth factor receptor-bound protein 7 |
| GRPR | gastrin-releasing peptide receptor |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AM | histone cluster 1, H2am |
| HOXA1 | homeobox A1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL33 | interleukin 33 |
| IL7 | interleukin 7 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KIF20A | kinesin family member 20A |
| KRT15 | keratin 15, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MED24 | mediator complex subunit 24 |
| MT1M | metallothionein 1M |
| MTA2 | metastasis associated 1 family, member 2 |
| MXD3 | MAX dimerization protein 3 |
| NAP1L3 | nucleosome assembly protein 1-like 3 |
| NKX3-2 | NK3 homeobox 2 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALMD | palmdelphin |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PLAT | plasminogen activator, tissue |
| PLAU | plasminogen activator, urokinase |
| PLK2 | polo-like kinase 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR15L | proline rich 15-like |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RGS2 | regulator of G-protein signaling 2 |
| RIT1 | Ras-like without CAAX 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCEL | sciellin |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SHROOM2 | shroom family member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SYT1 | synaptotagmin I |
| TAGLN3 | transgelin 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMSB15A | thymosin beta 15a |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRIB2 | tribbles pseudokinase 2 |
| TUBB2B | tubulin, beta 2B class IIb |
| VEGFC | vascular endothelial growth factor C |
| YPEL1 | yippee-like 1 (Drosophila) |
| YY2 | YY2 transcription factor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF528 | zinc finger protein 528 |
