rosiglitazone-5230 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the rosiglitazone-5230 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACOT11 acyl-CoA thioesterase 11
ACTC1 actin, alpha, cardiac muscle 1
AFAP1 actin filament associated protein 1
AGGF1 angiogenic factor with G patch and FHA domains 1
AMT aminomethyltransferase
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APC adenomatous polyposis coli
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPH aspartate beta-hydroxylase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BIK BCL2-interacting killer (apoptosis-inducing)
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF59 chromosome 17 open reading frame 59
C5AR2 complement component 5a receptor 2
CALCR calcitonin receptor
CALML5 calmodulin-like 5
CAPN10 calpain 10
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CCNT2 cyclin T2
CCPG1 cell cycle progression 1
CD1A CD1a molecule
CD52 CD52 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CTRL chymotrypsin-like
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPYS dihydropyrimidinase
DSTYK dual serine/threonine and tyrosine protein kinase
EFNA3 ephrin-A3
EPHA3 EPH receptor A3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPS8L3 EPS8-like 3
FAM169A family with sequence similarity 169, member A
FBXO4 F-box protein 4
FHL1 four and a half LIM domains 1
FLJ11710 uncharacterized protein FLJ11710
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GK3P glycerol kinase 3 pseudogene
GPR137 G protein-coupled receptor 137
HAP1 huntingtin-associated protein 1
HSF1 heat shock transcription factor 1
IFI6 interferon, alpha-inducible protein 6
ITM2C integral membrane protein 2C
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM4C lysine (K)-specific demethylase 4C
KLHL25 kelch-like family member 25
LINC00597 long intergenic non-protein coding RNA 597
MCOLN1 mucolipin 1
MED9 mediator complex subunit 9
METTL7A methyltransferase like 7A
MRPL44 mitochondrial ribosomal protein L44
MUC5B mucin 5B, oligomeric mucus/gel-forming
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NME5 NME/NM23 family member 5
NMT1 N-myristoyltransferase 1
PARD3 par-3 family cell polarity regulator
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
R3HDM1 R3H domain containing 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPL14 ribosomal protein L14
SDC3 syndecan 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD1B SET domain containing 1B
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNX13 sorting nexin 13
SPON2 spondin 2, extracellular matrix protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STARD3 StAR-related lipid transfer (START) domain containing 3
SYNGR1 synaptogyrin 1
TIGD6 tigger transposable element derived 6
TLE4 transducin-like enhancer of split 4
TRAFD1 TRAF-type zinc finger domain containing 1
TSPAN1 tetraspanin 1
TYRP1 tyrosinase-related protein 1
ULK2 unc-51 like autophagy activating kinase 2
WDR48 WD repeat domain 48
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
WDR78 WD repeat domain 78
ZFP64 ZFP64 zinc finger protein
ZNF16 zinc finger protein 16
ZNF573 zinc finger protein 573
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACTL8 actin-like 8
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARPIN actin-related protein 2/3 complex inhibitor
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BATF basic leucine zipper transcription factor, ATF-like
BMP15 bone morphogenetic protein 15
C14ORF93 chromosome 14 open reading frame 93
C17ORF80 chromosome 17 open reading frame 80
C1ORF35 chromosome 1 open reading frame 35
CCDC88C coiled-coil domain containing 88C
CCDC9 coiled-coil domain containing 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CEP97 centrosomal protein 97kDa
CFD complement factor D (adipsin)
CHML choroideremia-like (Rab escort protein 2)
CLCN6 chloride channel, voltage-sensitive 6
CLEC16A C-type lectin domain family 16, member A
CLSTN2 calsyntenin 2
CORO1A coronin, actin binding protein, 1A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRELD1 cysteine-rich with EGF-like domains 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DUSP2 dual specificity phosphatase 2
DVL1 dishevelled segment polarity protein 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ECHDC2 enoyl CoA hydratase domain containing 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHX2 epoxide hydrolase 2, cytoplasmic
FBXO31 F-box protein 31
FLCN folliculin
FRS2 fibroblast growth factor receptor substrate 2
GLRA1 glycine receptor, alpha 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR19 G protein-coupled receptor 19
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H3B histone cluster 1, H3b
HPS6 Hermansky-Pudlak syndrome 6
HSPA1L heat shock 70kDa protein 1-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLHL36 kelch-like family member 36
KREMEN2 kringle containing transmembrane protein 2
LARP6 La ribonucleoprotein domain family, member 6
LIME1 Lck interacting transmembrane adaptor 1
LRP5L low density lipoprotein receptor-related protein 5-like
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCOLN3 mucolipin 3
MDM4 MDM4, p53 regulator
MMP3 matrix metallopeptidase 3
MXD3 MAX dimerization protein 3
NPIPB3 nuclear pore complex interacting protein family, member B3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHEX phosphate regulating endopeptidase homolog, X-linked
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODNL1 podocan-like 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRPH peripherin
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB36 RAB36, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI14 retinoic acid induced 14
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RIN1 Ras and Rab interactor 1
S100A7 S100 calcium binding protein A7
SENP7 SUMO1/sentrin specific peptidase 7
SKI SKI proto-oncogene
SLC12A9 solute carrier family 12, member 9
SLC22A14 solute carrier family 22, member 14
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLIT2 slit homolog 2 (Drosophila)
SLMO1 slowmo homolog 1 (Drosophila)
SNAI2 snail family zinc finger 2
STAG3 stromal antigen 3
STBD1 starch binding domain 1
STON1 stonin 1
STRA6 stimulated by retinoic acid 6
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTA T-cell leukemia translocation altered
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM212 transmembrane protein 212
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
ZNF136 zinc finger protein 136
ZNF304 zinc finger protein 304
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747