rosiglitazone-5593 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the rosiglitazone-5593 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACAN aggrecan
ACTL8 actin-like 8
ACVR1B activin A receptor, type IB
ADAM19 ADAM metallopeptidase domain 19
ADAM23 ADAM metallopeptidase domain 23
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ANKH ANKH inorganic pyrophosphate transport regulator
APAF1 apoptotic peptidase activating factor 1
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTBD18 BTB (POZ) domain containing 18
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C2ORF27A chromosome 2 open reading frame 27A
C8A complement component 8, alpha polypeptide
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCL13 chemokine (C-C motif) ligand 13
CCL19 chemokine (C-C motif) ligand 19
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CYLD cylindromatosis (turban tumor syndrome)
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS12 dehydrogenase/reductase (SDR family) member 12
DNAH17 dynein, axonemal, heavy chain 17
DPYSL4 dihydropyrimidinase-like 4
DYSF dysferlin
EGFR epidermal growth factor receptor
EML2 echinoderm microtubule associated protein like 2
EPS8L3 EPS8-like 3
FAM182B family with sequence similarity 182, member B
FAXDC2 fatty acid hydroxylase domain containing 2
FCMR Fc fragment of IgM receptor
FRMD8 FERM domain containing 8
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GP2 glycoprotein 2 (zymogen granule membrane)
GPATCH4 G patch domain containing 4
GRM6 glutamate receptor, metabotropic 6
GSK3A glycogen synthase kinase 3 alpha
GSTA3 glutathione S-transferase alpha 3
HAB1 B1 for mucin
HBB hemoglobin, beta
HGFAC HGF activator
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HRH3 histamine receptor H3
HSF2BP heat shock transcription factor 2 binding protein
IFNA14 interferon, alpha 14
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITM2C integral membrane protein 2C
KANK1 KN motif and ankyrin repeat domains 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LINC00574 long intergenic non-protein coding RNA 574
LMTK1 lemur tail kinase 1
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRP12 low density lipoprotein receptor-related protein 12
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEG3 maternally expressed 3 (non-protein coding)
MFSD7 major facilitator superfamily domain containing 7
MIER2 mesoderm induction early response 1, family member 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTSS1L metastasis suppressor 1-like
MYBPC3 myosin binding protein C, cardiac
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OMG oligodendrocyte myelin glycoprotein
PAPPA2 pappalysin 2
PCDHGB6 protocadherin gamma subfamily B, 6
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLG plasminogen
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTCRA pre T-cell antigen receptor alpha
PTPRJ protein tyrosine phosphatase, receptor type, J
PVR poliovirus receptor
RAPSN receptor-associated protein of the synapse
RFPL1S RFPL1 antisense RNA 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
STS steroid sulfatase (microsomal), isozyme S
SYNGR1 synaptogyrin 1
THBS1 thrombospondin 1
THSD4 thrombospondin, type I, domain containing 4
TM4SF20 transmembrane 4 L six family member 20
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPM2 tropomyosin 2 (beta)
TSC22D2 TSC22 domain family, member 2
YY2 YY2 transcription factor
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ABHD17B abhydrolase domain containing 17B
ACBD4 acyl-CoA binding domain containing 4
ARPIN actin-related protein 2/3 complex inhibitor
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCAS1 breast carcinoma amplified sequence 1
BHLHE41 basic helix-loop-helix family, member e41
BTF3P12 basic transcription factor 3 pseudogene 12
C1QTNF3 C1q and tumor necrosis factor related protein 3
CBX8 chromobox homolog 8
CCDC121 coiled-coil domain containing 121
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHKB choline kinase beta
CHM choroideremia (Rab escort protein 1)
CHML choroideremia-like (Rab escort protein 2)
CLDN15 claudin 15
CRYL1 crystallin, lambda 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOC2A double C2-like domains, alpha
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM155B family with sequence similarity 155, member B
FAM204A family with sequence similarity 204, member A
FAM53B family with sequence similarity 53, member B
FGF6 fibroblast growth factor 6
FMO4 flavin containing monooxygenase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GATA4 GATA binding protein 4
GPATCH2L G patch domain containing 2-like
HDAC11 histone deacetylase 11
HDAC5 histone deacetylase 5
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT54 intraflagellar transport 54
INF2 inverted formin, FH2 and WH2 domain containing
IQCC IQ motif containing C
KCNIP1 Kv channel interacting protein 1
LIME1 Lck interacting transmembrane adaptor 1
LOC390998 ribosomal protein L10 pseudogene
LZTS3 leucine zipper, putative tumor suppressor family member 3
MATK megakaryocyte-associated tyrosine kinase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NTF3 neurotrophin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT2 one cut homeobox 2
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PAX9 paired box 9
PCDHA9 protocadherin alpha 9
POM121 POM121 transmembrane nucleoporin
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRSS53 protease, serine, 53
RIPK4 receptor-interacting serine-threonine kinase 4
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
RPGRIP1L RPGRIP1-like
SAMD9 sterile alpha motif domain containing 9
SDC3 syndecan 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD1A SET domain containing 1A
SGMS1 sphingomyelin synthase 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SIRT2 sirtuin 2
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SUSD6 sushi domain containing 6
TDRKH tudor and KH domain containing
TM7SF3 transmembrane 7 superfamily member 3
TPK1 thiamin pyrophosphokinase 1
TSPYL2 TSPY-like 2
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VGF VGF nerve growth factor inducible
VIM vimentin
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XYLT1 xylosyltransferase I
ZFHX2 zinc finger homeobox 2
ZNF23 zinc finger protein 23
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862