rosiglitazone-6950 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the rosiglitazone-6950 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALPK1 alpha-kinase 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BGN biglycan
BLVRA biliverdin reductase A
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF59 chromosome 17 open reading frame 59
CDC14B cell division cycle 14B
CEP104 centrosomal protein 104kDa
CEP162 centrosomal protein 162kDa
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CPT1A carnitine palmitoyltransferase 1A (liver)
CRLF1 cytokine receptor-like factor 1
CSHL1 chorionic somatomammotropin hormone-like 1
CTBS chitobiase, di-N-acetyl-
CXCL8 chemokine (C-X-C motif) ligand 8
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DACH1 dachshund family transcription factor 1
DALRD3 DALR anticodon binding domain containing 3
DCBLD2 discoidin, CUB and LCCL domain containing 2
DFNB31 deafness, autosomal recessive 31
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAH3 dynein, axonemal, heavy chain 3
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DTX2 deltex 2, E3 ubiquitin ligase
DUSP13 dual specificity phosphatase 13
EHD2 EH-domain containing 2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPOR erythropoietin receptor
ERCC6 excision repair cross-complementation group 6
FAS Fas cell surface death receptor
FCF1 FCF1 rRNA-processing protein
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF6 fibroblast growth factor 6
FLJ21369 uncharacterized protein FLJ21369
GFI1 growth factor independent 1 transcription repressor
GNAS GNAS complex locus
GPC3 glypican 3
HIST1H2AI histone cluster 1, H2ai
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFT38 intraflagellar transport 38
IL1RN interleukin 1 receptor antagonist
ING1 inhibitor of growth family, member 1
KANSL3 KAT8 regulatory NSL complex subunit 3
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KDM4B lysine (K)-specific demethylase 4B
KLF5 Kruppel-like factor 5 (intestinal)
KRT12 keratin 12, type I
LBX1 ladybird homeobox 1
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC399491
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MYO15A myosin XVA
MYOF myoferlin
NCKAP1 NCK-associated protein 1
NFX1 nuclear transcription factor, X-box binding 1
NFYA nuclear transcription factor Y, alpha
NKX3-2 NK3 homeobox 2
NLGN1 neuroligin 1
NXT2 nuclear transport factor 2-like export factor 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PASK PAS domain containing serine/threonine kinase
PCDHB17P protocadherin beta 17 pseudogene
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAA phospholipase A2-activating protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PRB3 proline-rich protein BstNI subfamily 3
PRKCA protein kinase C, alpha
RB1 retinoblastoma 1
RHEB Ras homolog enriched in brain
RNF19B ring finger protein 19B
RNF24 ring finger protein 24
RNF6 ring finger protein (C3H2C3 type) 6
RNFT1 ring finger protein, transmembrane 1
RPS3A ribosomal protein S3A
SEC63 SEC63 homolog (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIK2 salt-inducible kinase 2
SIX3 SIX homeobox 3
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SSX1 synovial sarcoma, X breakpoint 1
SSX3 synovial sarcoma, X breakpoint 3
STON1 stonin 1
STX6 syntaxin 6
STYK1 serine/threonine/tyrosine kinase 1
TCP10L t-complex 10-like
TRIO trio Rho guanine nucleotide exchange factor
TUBGCP3 tubulin, gamma complex associated protein 3
WDR91 WD repeat domain 91
XDH xanthine dehydrogenase
ZNF318 zinc finger protein 318
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACVR2B activin A receptor, type IIB
AKR1C3 aldo-keto reductase family 1, member C3
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC6 armadillo repeat containing 6
BEX4 brain expressed, X-linked 4
C16ORF59 chromosome 16 open reading frame 59
CAPG capping protein (actin filament), gelsolin-like
CBX7 chromobox homolog 7
CCDC88C coiled-coil domain containing 88C
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEP131 centrosomal protein 131kDa
CFD complement factor D (adipsin)
CHPF chondroitin polymerizing factor
CHST10 carbohydrate sulfotransferase 10
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
COCH cochlin
CORO2A coronin, actin binding protein, 2A
CRABP1 cellular retinoic acid binding protein 1
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDC3 enhancer of mRNA decapping 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM131A family with sequence similarity 131, member A
FHOD1 formin homology 2 domain containing 1
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOSL1 FOS-like antigen 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GAN gigaxonin
GDAP2 ganglioside induced differentiation associated protein 2
GPR87 G protein-coupled receptor 87
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTPBP6 GTP binding protein 6 (putative)
HIRA histone cell cycle regulator
HYAL2 hyaluronoglucosaminidase 2
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
JMJD1C jumonji domain containing 1C
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0753 KIAA0753
LRRC20 leucine rich repeat containing 20
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
LZTFL1 leucine zipper transcription factor-like 1
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL46 mitochondrial ribosomal protein L46
MTMR11 myotubularin related protein 11
MTSS1L metastasis suppressor 1-like
OXTR oxytocin receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PGPEP1 pyroglutamyl-peptidase I
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PODXL2 podocalyxin-like 2
RAB3A RAB3A, member RAS oncogene family
RIBC2 RIB43A domain with coiled-coils 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCN1B sodium channel, voltage gated, type I beta subunit
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPIDR scaffolding protein involved in DNA repair
STARD5 StAR-related lipid transfer (START) domain containing 5
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D17 TBC1 domain family, member 17
TCTN2 tectonic family member 2
THAP1 THAP domain containing, apoptosis associated protein 1
THAP7 THAP domain containing 7
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM254 transmembrane protein 254
TNRC6B trinucleotide repeat containing 6B
TRIM5 tripartite motif containing 5
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UBTD1 ubiquitin domain containing 1
USP18 ubiquitin specific peptidase 18
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF324 zinc finger protein 324
ZNF767P zinc finger family member 767, pseudogene