| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the rotenone-5915 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| AEBP1 | AE binding protein 1 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ATP10B | ATPase, class V, type 10B |
| ATP9A | ATPase, class II, type 9A |
| BCAP29 | B-cell receptor-associated protein 29 |
| BMP1 | bone morphogenetic protein 1 |
| BMP2K | BMP2 inducible kinase |
| C6 | complement component 6 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD209 | CD209 molecule |
| CDC14A | cell division cycle 14A |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLDN11 | claudin 11 |
| COL4A1 | collagen, type IV, alpha 1 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CPB2 | carboxypeptidase B2 (plasma) |
| DAPK2 | death-associated protein kinase 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DOCK6 | dedicator of cytokinesis 6 |
| ECE1 | endothelin converting enzyme 1 |
| EHD2 | EH-domain containing 2 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| EMC1 | ER membrane protein complex subunit 1 |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FH | fumarate hydratase |
| GAMT | guanidinoacetate N-methyltransferase |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPATCH2L | G patch domain containing 2-like |
| GSK3A | glycogen synthase kinase 3 alpha |
| HIST1H2BN | histone cluster 1, H2bn |
| HMGA2 | high mobility group AT-hook 2 |
| IL22 | interleukin 22 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIF25 | kinesin family member 25 |
| KLF6 | Kruppel-like factor 6 |
| KLK3 | kallikrein-related peptidase 3 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MINK1 | misshapen-like kinase 1 |
| MR1 | major histocompatibility complex, class I-related |
| MSMB | microseminoprotein, beta- |
| MYL10 | myosin, light chain 10, regulatory |
| NIPAL2 | NIPA-like domain containing 2 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NOTCH4 | notch 4 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDLIM4 | PDZ and LIM domain 4 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PTCRA | pre T-cell antigen receptor alpha |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RABGAP1L | RAB GTPase activating protein 1-like |
| REST | RE1-silencing transcription factor |
| RIF1 | replication timing regulatory factor 1 |
| RND1 | Rho family GTPase 1 |
| RNF39 | ring finger protein 39 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| S100A13 | S100 calcium binding protein A13 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPN | sialophorin |
| STEAP4 | STEAP family member 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCP11 | t-complex 11, testis-specific |
| TCTN2 | tectonic family member 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNS1 | tensin 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRD | T cell receptor delta locus |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| VGF | VGF nerve growth factor inducible |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AEN | apoptosis enhancing nuclease |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARMC4 | armadillo repeat containing 4 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| AUTS2 | autism susceptibility candidate 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CASD1 | CAS1 domain containing 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DEPDC5 | DEP domain containing 5 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUX1 | double homeobox 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EXOSC1 | exosome component 1 |
| FAM155B | family with sequence similarity 155, member B |
| FAM169A | family with sequence similarity 169, member A |
| FAM204A | family with sequence similarity 204, member A |
| FRMD1 | FERM domain containing 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H2AB | histone cluster 1, H2ab |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3I | histone cluster 1, H3i |
| HOXC5 | homeobox C5 |
| IL4R | interleukin 4 receptor |
| ITM2C | integral membrane protein 2C |
| KIAA0125 | KIAA0125 |
| KIAA1456 | KIAA1456 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEGF8 | multiple EGF-like-domains 8 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MMRN2 | multimerin 2 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PALM | paralemmin |
| PCDHB12 | protocadherin beta 12 |
| PCDHB13 | protocadherin beta 13 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PGR | progesterone receptor |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PITX2 | paired-like homeodomain 2 |
| PLD2 | phospholipase D2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKD3 | protein kinase D3 |
| PROS1 | protein S (alpha) |
| PRR34 | proline rich 34 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPL10L | ribosomal protein L10-like |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCHIP1 | schwannomin interacting protein 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SKI | SKI proto-oncogene |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPRYD7 | SPRY domain containing 7 |
| STX1A | syntaxin 1A (brain) |
| TAOK1 | TAO kinase 1 |
| TCHH | trichohyalin |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM242 | transmembrane protein 242 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TPSG1 | tryptase gamma 1 |
| TRABD | TraB domain containing |
| TRIM5 | tripartite motif containing 5 |
| TSGA10 | testis specific, 10 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF286A | zinc finger protein 286A |
| ZNF324 | zinc finger protein 324 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
