rotenone-5943 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the rotenone-5943 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALCAM activated leukocyte cell adhesion molecule
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALPK1 alpha-kinase 1
ANGEL2 angel homolog 2 (Drosophila)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF3 activating transcription factor 3
C10ORF12 chromosome 10 open reading frame 12
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CARD9 caspase recruitment domain family, member 9
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN6 chloride channel, voltage-sensitive 6
CLCN7 chloride channel, voltage-sensitive 7
CPQ carboxypeptidase Q
CTIF CBP80/20-dependent translation initiation factor
DCTN1 dynactin 1
DOC2A double C2-like domains, alpha
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDRF1 erythroid differentiation regulatory factor 1
EFNA3 ephrin-A3
ELAVL1 ELAV like RNA binding protein 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
FAM53B family with sequence similarity 53, member B
FBXL2 F-box and leucine-rich repeat protein 2
FLJ11710 uncharacterized protein FLJ11710
FSCN1 fascin actin-bundling protein 1
GMPR guanosine monophosphate reductase
GPR161 G protein-coupled receptor 161
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HFE hemochromatosis
HHAT hedgehog acyltransferase
HPS1 Hermansky-Pudlak syndrome 1
ICA1 islet cell autoantigen 1, 69kDa
ING1 inhibitor of growth family, member 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KAZN kazrin, periplakin interacting protein
KIAA1456 KIAA1456
KIF22 kinesin family member 22
LIN7A lin-7 homolog A (C. elegans)
LIN7B lin-7 homolog B (C. elegans)
LPIN2 lipin 2
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO1E myosin IE
NCAPH2 non-SMC condensin II complex, subunit H2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPR3 natriuretic peptide receptor 3
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
OSMR oncostatin M receptor
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDLIM5 PDZ and LIM domain 5
POPDC3 popeye domain containing 3
PRB1 proline-rich protein BstNI subfamily 1
PTMS parathymosin
RAB11B RAB11B, member RAS oncogene family
RBM5 RNA binding motif protein 5
REEP2 receptor accessory protein 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SAPCD1 suppressor APC domain containing 1
SERHL2 serine hydrolase-like 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOGA1 suppressor of glucose, autophagy associated 1
SPRY4 sprouty homolog 4 (Drosophila)
SPRYD7 SPRY domain containing 7
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STK4 serine/threonine kinase 4
TH tyrosine hydroxylase
TMEM121 transmembrane protein 121
TMEM206 transmembrane protein 206
TMPRSS2 transmembrane protease, serine 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TTLL7 tubulin tyrosine ligase-like family member 7
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAC14 Vac14 homolog (S. cerevisiae)
VEGFA vascular endothelial growth factor A
VGF VGF nerve growth factor inducible
WDTC1 WD and tetratricopeptide repeats 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF197 zinc finger protein 197

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTA1 actin, alpha 1, skeletal muscle
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKRD7 ankyrin repeat domain 7
ARC activity-regulated cytoskeleton-associated protein
ATG10 autophagy related 10
BCO1 beta-carotene oxygenase 1
C2ORF27A chromosome 2 open reading frame 27A
CCNJL cyclin J-like
CD34 CD34 molecule
CD83 CD83 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDCP1 CUB domain containing protein 1
CDH10 cadherin 10, type 2 (T2-cadherin)
CDON cell adhesion associated, oncogene regulated
CEND1 cell cycle exit and neuronal differentiation 1
CLSTN2 calsyntenin 2
CSF1R colony stimulating factor 1 receptor
CUZD1 CUB and zona pellucida-like domains 1
EAF2 ELL associated factor 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGLN3 egl-9 family hypoxia-inducible factor 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
F13A1 coagulation factor XIII, A1 polypeptide
FAM124B family with sequence similarity 124B
FAM76A family with sequence similarity 76, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBRS fibrosin
FBXL8 F-box and leucine-rich repeat protein 8
FBXO2 F-box protein 2
FGF23 fibroblast growth factor 23
FMOD fibromodulin
FOXN2 forkhead box N2
GEM GTP binding protein overexpressed in skeletal muscle
GEMIN8 gem (nuclear organelle) associated protein 8
HCRTR2 hypocretin (orexin) receptor 2
HIST1H2AJ histone cluster 1, H2aj
HOXB2 homeobox B2
HOXC5 homeobox C5
HOXD11 homeobox D11
HYI hydroxypyruvate isomerase (putative)
INHA inhibin, alpha
INSIG2 insulin induced gene 2
IRF1 interferon regulatory factor 1
IRF8 interferon regulatory factor 8
JAM3 junctional adhesion molecule 3
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00115 long intergenic non-protein coding RNA 115
LINC00341 long intergenic non-protein coding RNA 341
LRRC20 leucine rich repeat containing 20
LTC4S leukotriene C4 synthase
MAL mal, T-cell differentiation protein
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED31 mediator complex subunit 31
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRPL41 mitochondrial ribosomal protein L41
MTCP1 mature T-cell proliferation 1
MYO15A myosin XVA
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
OLFML2B olfactomedin-like 2B
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PENK proenkephalin
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCH2 phospholipase C, eta 2
POLM polymerase (DNA directed), mu
POM121L2 POM121 transmembrane nucleoporin-like 2
POU3F2 POU class 3 homeobox 2
PTPRH protein tyrosine phosphatase, receptor type, H
RASL11B RAS-like, family 11, member B
RPS4Y1 ribosomal protein S4, Y-linked 1
SCG5 secretogranin V
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SIX3 SIX homeobox 3
SKAP1 src kinase associated phosphoprotein 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLN sarcolipin
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
STAG3 stromal antigen 3
SULT4A1 sulfotransferase family 4A, member 1
TAGLN3 transgelin 3
TBC1D2 TBC1 domain family, member 2
TRIM25 tripartite motif containing 25
TRIM36 tripartite motif containing 36
UCN urocortin
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZBTB3 zinc finger and BTB domain containing 3
ZBTB6 zinc finger and BTB domain containing 6
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFHX4 zinc finger homeobox 4
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF506 zinc finger protein 506
ZNF669 zinc finger protein 669