rotenone Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica). (Chemical Entities of Biological Interest Ontology, CHEBI_28201)
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Genes

9 genes co-occuring with the biological term rotenone in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ATG5 autophagy related 5
BAX BCL2-associated X protein
CRTC3 CREB regulated transcription coactivator 3
CYBB cytochrome b-245, beta polypeptide
FTMT ferritin mitochondrial
HTRA2 HtrA serine peptidase 2
LRRK2 leucine-rich repeat kinase 2
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)