| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the rottlerin-825 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGB | androglobin |
| AGXT | alanine-glyoxylate aminotransferase |
| ALOX12 | arachidonate 12-lipoxygenase |
| APOE | apolipoprotein E |
| ATF3 | activating transcription factor 3 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CASS4 | Cas scaffolding protein family member 4 |
| CDC14B | cell division cycle 14B |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLDN14 | claudin 14 |
| CLDN17 | claudin 17 |
| COL6A1 | collagen, type VI, alpha 1 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CSN2 | casein beta |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUX4L8 | double homeobox 4 like 8 |
| EFS | embryonal Fyn-associated substrate |
| EPB41 | erythrocyte membrane protein band 4.1 |
| FAM120C | family with sequence similarity 120C |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FLJ11292 | |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GK | glycerol kinase |
| GPR153 | G protein-coupled receptor 153 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IDS | iduronate 2-sulfatase |
| IL15RA | interleukin 15 receptor, alpha |
| INHBE | inhibin, beta E |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KIF1A | kinesin family member 1A |
| KLHDC8A | kelch domain containing 8A |
| KLHL24 | kelch-like family member 24 |
| KRTAP1-3 | keratin associated protein 1-3 |
| LAMA4 | laminin, alpha 4 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAOA | monoamine oxidase A |
| MAP1A | microtubule-associated protein 1A |
| MCF2 | MCF.2 cell line derived transforming sequence |
| MIR622 | microRNA 622 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NAIP | NLR family, apoptosis inhibitory protein |
| NKTR | natural killer cell triggering receptor |
| NLRP3 | NLR family, pyrin domain containing 3 |
| NME8 | NME/NM23 family member 8 |
| NMT2 | N-myristoyltransferase 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PEG10 | paternally expressed 10 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLVAP | plasmalemma vesicle associated protein |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| RBBP4 | retinoblastoma binding protein 4 |
| RBMY2FP | RNA binding motif protein, Y-linked, family 2, member F pseudogene |
| RECQL5 | RecQ protein-like 5 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| SCEL | sciellin |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOCS2 | suppressor of cytokine signaling 2 |
| STK38L | serine/threonine kinase 38 like |
| STOM | stomatin |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TGFA | transforming growth factor, alpha |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRGV5 | T cell receptor gamma variable 5 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WSCD1 | WSC domain containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BRD1 | bromodomain containing 1 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC88C | coiled-coil domain containing 88C |
| CEP131 | centrosomal protein 131kDa |
| CFD | complement factor D (adipsin) |
| CHMP6 | charged multivesicular body protein 6 |
| CHPF | chondroitin polymerizing factor |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLK4 | CDC-like kinase 4 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CUL1 | cullin 1 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FADS3 | fatty acid desaturase 3 |
| FILIP1L | filamin A interacting protein 1-like |
| FOXC1 | forkhead box C1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FXN | frataxin |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HOXC10 | homeobox C10 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| JMJD1C | jumonji domain containing 1C |
| KIAA0922 | KIAA0922 |
| KLHL2 | kelch-like family member 2 |
| KRBOX4 | KRAB box domain containing 4 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NES | nestin |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NKRF | NFKB repressing factor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G15 | phospholipase A2, group XV |
| PLIN3 | perilipin 3 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRKX | protein kinase, X-linked |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RBM42 | RNA binding motif protein 42 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RNF38 | ring finger protein 38 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SESN1 | sestrin 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC35E3 | solute carrier family 35, member E3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SP1 | Sp1 transcription factor |
| SPAG1 | sperm associated antigen 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SSFA2 | sperm specific antigen 2 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM45 | tripartite motif containing 45 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VASH1 | vasohibin 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR37 | WD repeat domain 37 |
| WDR46 | WD repeat domain 46 |
| WDR76 | WD repeat domain 76 |
| WRAP73 | WD repeat containing, antisense to TP73 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF254 | zinc finger protein 254 |
| ZNF268 | zinc finger protein 268 |
| ZNF721 | zinc finger protein 721 |
| ZNF778 | zinc finger protein 778 |
