| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the rottlerin-914 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AFAP1 | actin filament associated protein 1 |
| AK1 | adenylate kinase 1 |
| ANKRD6 | ankyrin repeat domain 6 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| APOM | apolipoprotein M |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATF3 | activating transcription factor 3 |
| ATN1 | atrophin 1 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| BAG4 | BCL2-associated athanogene 4 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BTD | biotinidase |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CA4 | carbonic anhydrase IV |
| CCPG1 | cell cycle progression 1 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLGN | calmegin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CUL9 | cullin 9 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FNDC3A | fibronectin type III domain containing 3A |
| FOXO1 | forkhead box O1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GFI1 | growth factor independent 1 transcription repressor |
| GOLGA2 | golgin A2 |
| GRB10 | growth factor receptor-bound protein 10 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSPT1 | G1 to S phase transition 1 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H3B | histone cluster 1, H3b |
| HPR | haptoglobin-related protein |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| IFIH1 | interferon induced with helicase C domain 1 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INADL | InaD-like (Drosophila) |
| ING4 | inhibitor of growth family, member 4 |
| INHBE | inhibin, beta E |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA1109 | KIAA1109 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LIMCH1 | LIM and calponin homology domains 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC40 | leucine rich repeat containing 40 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1B | microtubule-associated protein 1B |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MOSPD3 | motile sperm domain containing 3 |
| NEBL | nebulette |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) |
| NLGN1 | neuroligin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PACRG | PARK2 co-regulated |
| PADI4 | peptidyl arginine deiminase, type IV |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PSPH | phosphoserine phosphatase |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RNF208 | ring finger protein 208 |
| RPL7 | ribosomal protein L7 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST20 | suppressor of tumorigenicity 20 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STIM1 | stromal interaction molecule 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TCTN2 | tectonic family member 2 |
| TMEM212 | transmembrane protein 212 |
| TRIB3 | tribbles pseudokinase 3 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF365 | zinc finger protein 365 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ACVR2B | activin A receptor, type IIB |
| ADCY6 | adenylate cyclase 6 |
| ANO10 | anoctamin 10 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CCNO | cyclin O |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPO | centromere protein O |
| CHKB | choline kinase beta |
| CORO1A | coronin, actin binding protein, 1A |
| CORT | cortistatin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DENND1B | DENN/MADD domain containing 1B |
| EFNA4 | ephrin-A4 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F8 | coagulation factor VIII, procoagulant component |
| FBXO5 | F-box protein 5 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FICD | FIC domain containing |
| FMO4 | flavin containing monooxygenase 4 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GHR | growth hormone receptor |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H3G | histone cluster 1, H3g |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IPP | intracisternal A particle-promoted polypeptide |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KRT15 | keratin 15, type I |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP1S | microtubule-associated protein 1S |
| MAPK12 | mitogen-activated protein kinase 12 |
| MISP | mitotic spindle positioning |
| MSX1 | msh homeobox 1 |
| MT1H | metallothionein 1H |
| MVD | mevalonate (diphospho) decarboxylase |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NDE1 | nudE neurodevelopment protein 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NLK | nemo-like kinase |
| NMU | neuromedin U |
| NPY1R | neuropeptide Y receptor Y1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCBP4 | poly(rC) binding protein 4 |
| PCDHB3 | protocadherin beta 3 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PGR | progesterone receptor |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMP22 | peripheral myelin protein 22 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTGES2 | prostaglandin E synthase 2 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBM14 | RNA binding motif protein 14 |
| SALL2 | spalt-like transcription factor 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SETD6 | SET domain containing 6 |
| SH2D4A | SH2 domain containing 4A |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| TARP | TCR gamma alternate reading frame protein |
| TEFM | transcription elongation factor, mitochondrial |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMC5 | transmembrane channel-like 5 |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM62 | transmembrane protein 62 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UBXN6 | UBX domain protein 6 |
| UNKL | unkempt family zinc finger-like |
| VASH1 | vasohibin 1 |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF254 | zinc finger protein 254 |
| ZNF276 | zinc finger protein 276 |
| ZNF586 | zinc finger protein 586 |
| ZNF76 | zinc finger protein 76 |
| ZW10 | zw10 kinetochore protein |
