| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the rottlerin-941 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMOTL2 | angiomotin like 2 |
| AREG | amphiregulin |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP164 | centrosomal protein 164kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLGN | calmegin |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTAGE5 | CTAGE family, member 5 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP10 | dual specificity phosphatase 10 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGR1 | early growth response 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV5 | ets variant 5 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSL2 | FOS-like antigen 2 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLS | glutaminase |
| GRB7 | growth factor receptor-bound protein 7 |
| GTPBP2 | GTP binding protein 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST2H2BE | histone cluster 2, H2be |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1B | microtubule-associated protein 1B |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MARS | methionyl-tRNA synthetase |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MED6 | mediator complex subunit 6 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| SAMD4A | sterile alpha motif domain containing 4A |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMAD3 | SMAD family member 3 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SQSTM1 | sequestosome 1 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STRN | striatin, calmodulin binding protein |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM36 | tripartite motif containing 36 |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZNF165 | zinc finger protein 165 |
| ZNF329 | zinc finger protein 329 |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ARMC7 | armadillo repeat containing 7 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| BAK1 | BCL2-antagonist/killer 1 |
| BAX | BCL2-associated X protein |
| BCL9 | B-cell CLL/lymphoma 9 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BMP4 | bone morphogenetic protein 4 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CERK | ceramide kinase |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CPTP | ceramide-1-phosphate transfer protein |
| CROT | carnitine O-octanoyltransferase |
| CTSV | cathepsin V |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DUSP8 | dual specificity phosphatase 8 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| E2F8 | E2F transcription factor 8 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAM172A | family with sequence similarity 172, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| FMO4 | flavin containing monooxygenase 4 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GHR | growth hormone receptor |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GPALPP1 | GPALPP motifs containing 1 |
| GPR137B | G protein-coupled receptor 137B |
| GPR19 | G protein-coupled receptor 19 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPA2 | heat shock 70kDa protein 2 |
| ICK | intestinal cell (MAK-like) kinase |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF3A | kinesin family member 3A |
| KIFC1 | kinesin family member C1 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LMNB1 | lamin B1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAGEH1 | melanoma antigen family H1 |
| MAP6D1 | MAP6 domain containing 1 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MCM10 | minichromosome maintenance complex component 10 |
| METTL2B | methyltransferase like 2B |
| MMP9 | matrix metallopeptidase 9 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PDZD8 | PDZ domain containing 8 |
| PER3 | period circadian clock 3 |
| PFDN6 | prefoldin subunit 6 |
| PGP | phosphoglycolate phosphatase |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RANBP6 | RAN binding protein 6 |
| RBL1 | retinoblastoma-like 1 |
| RBM12 | RNA binding motif protein 12 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SIRT2 | sirtuin 2 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM110 | transmembrane protein 110 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF107 | zinc finger protein 107 |
| ZNF160 | zinc finger protein 160 |
| ZNF271P | zinc finger protein 271, pseudogene |
| ZNF430 | zinc finger protein 430 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
