rottlerin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis. (Chemical Entities of Biological Interest Ontology, CHEBI_8899)
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Genes

11 genes co-occuring with the biological term rottlerin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BIRC5 baculoviral IAP repeat containing 5
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CDK1 cyclin-dependent kinase 1
LRP6 low density lipoprotein receptor-related protein 6
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PRKCD protein kinase C, delta
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase