| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the roxarsone-2950 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| ACTN2 | actinin, alpha 2 |
| ACVR1B | activin A receptor, type IB |
| ADCY2 | adenylate cyclase 2 (brain) |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ATG10 | autophagy related 10 |
| ATXN2L | ataxin 2-like |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA6 | carbonic anhydrase VI |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CDC25C | cell division cycle 25C |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| COL1A1 | collagen, type I, alpha 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTSF | cathepsin F |
| DAGLA | diacylglycerol lipase, alpha |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DIO2 | deiodinase, iodothyronine, type II |
| DLG5 | discs, large homolog 5 (Drosophila) |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FAM120C | family with sequence similarity 120C |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FOXD1 | forkhead box D1 |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GCH1 | GTP cyclohydrolase 1 |
| GMPR | guanosine monophosphate reductase |
| GPATCH2L | G patch domain containing 2-like |
| HAB1 | B1 for mucin |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HNMT | histamine N-methyltransferase |
| HOMER3 | homer scaffolding protein 3 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IHH | indian hedgehog |
| JAK3 | Janus kinase 3 |
| JAM3 | junctional adhesion molecule 3 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBD2 | methyl-CpG binding domain protein 2 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) |
| MED25 | mediator complex subunit 25 |
| MEFV | Mediterranean fever |
| MLPH | melanophilin |
| MSRB2 | methionine sulfoxide reductase B2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFRKB | nuclear factor related to kappaB binding protein |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) |
| PCGF2 | polycomb group ring finger 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PEX6 | peroxisomal biogenesis factor 6 |
| PLXNA1 | plexin A1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRKCE | protein kinase C, epsilon |
| RAB6B | RAB6B, member RAS oncogene family |
| RASA3 | RAS p21 protein activator 3 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYT12 | synaptotagmin XII |
| TBXA2R | thromboxane A2 receptor |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFR2 | transferrin receptor 2 |
| THBS3 | thrombospondin 3 |
| TJP1 | tight junction protein 1 |
| TM2D1 | TM2 domain containing 1 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM212 | transmembrane protein 212 |
| TNC | tenascin C |
| TRPS1 | trichorhinophalangeal syndrome I |
| WWC1 | WW and C2 domain containing 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF43 | zinc finger protein 43 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AGO1 | argonaute RISC catalytic component 1 |
| AIM2 | absent in melanoma 2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARMC6 | armadillo repeat containing 6 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BAK1 | BCL2-antagonist/killer 1 |
| CD82 | CD82 molecule |
| CD9 | CD9 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYBRD1 | cytochrome b reductase 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| FHIT | fragile histidine triad |
| FKBPL | FK506 binding protein like |
| FMO4 | flavin containing monooxygenase 4 |
| FZD2 | frizzled class receptor 2 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HCFC2 | host cell factor C2 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIRA | histone cell cycle regulator |
| HIST1H4D | histone cluster 1, H4d |
| HRH1 | histamine receptor H1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRF9 | interferon regulatory factor 9 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGB7 | integrin, beta 7 |
| JUNB | jun B proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MX1 | MX dynamin-like GTPase 1 |
| NECAP2 | NECAP endocytosis associated 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLCB4 | phospholipase C, beta 4 |
| POMT1 | protein-O-mannosyltransferase 1 |
| POMZP3 | POM121 and ZP3 fusion |
| POR | P450 (cytochrome) oxidoreductase |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PSKH1 | protein serine kinase H1 |
| QSER1 | glutamine and serine rich 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SASH3 | SAM and SH3 domain containing 3 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC38A6 | solute carrier family 38, member 6 |
| SNX16 | sorting nexin 16 |
| SP1 | Sp1 transcription factor |
| SP140L | SP140 nuclear body protein-like |
| STX17 | syntaxin 17 |
| STX5 | syntaxin 5 |
| SUSD6 | sushi domain containing 6 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TESK2 | testis-specific kinase 2 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM159 | transmembrane protein 159 |
| TRAPPC2L | trafficking protein particle complex 2-like |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPYL2 | TSPY-like 2 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR13 | WD repeat domain 13 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZFP30 | ZFP30 zinc finger protein |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF175 | zinc finger protein 175 |
| ZNF232 | zinc finger protein 232 |
| ZNF282 | zinc finger protein 282 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF675 | zinc finger protein 675 |
| ZNF701 | zinc finger protein 701 |
