roxarsone-3511 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the roxarsone-3511 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM22 ADAM metallopeptidase domain 22
ADCK4 aarF domain containing kinase 4
ADGRA2 adhesion G protein-coupled receptor A2
AKAP8L A kinase (PRKA) anchor protein 8-like
APOE apolipoprotein E
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP11A ATPase, class VI, type 11A
ATXN8OS ATXN8 opposite strand (non-protein coding)
AUTS2 autism susceptibility candidate 2
BHLHE40 basic helix-loop-helix family, member e40
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C2ORF72 chromosome 2 open reading frame 72
CARD9 caspase recruitment domain family, member 9
CAV2 caveolin 2
CCDC22 coiled-coil domain containing 22
CCDC57 coiled-coil domain containing 57
CCDC85B coiled-coil domain containing 85B
CD36 CD36 molecule (thrombospondin receptor)
CES3 carboxylesterase 3
CHM choroideremia (Rab escort protein 1)
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR6 chemokine (C-X-C motif) receptor 6
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DAPK1 death-associated protein kinase 1
DBT dihydrolipoamide branched chain transacylase E2
DNAH17 dynein, axonemal, heavy chain 17
DNASE1L2 deoxyribonuclease I-like 2
DPP4 dipeptidyl-peptidase 4
EDA ectodysplasin A
ELL2 elongation factor, RNA polymerase II, 2
EXOSC2 exosome component 2
FOXG1 forkhead box G1
FOXI1 forkhead box I1
FOXN3 forkhead box N3
FSTL3 follistatin-like 3 (secreted glycoprotein)
FYB FYN binding protein
GLDC glycine dehydrogenase (decarboxylating)
GLS glutaminase
GSPT2 G1 to S phase transition 2
HAO2 hydroxyacid oxidase 2 (long chain)
HOXB3 homeobox B3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICOSLG inducible T-cell co-stimulator ligand
IFI44 interferon-induced protein 44
IGL immunoglobulin lambda locus
IPO8 importin 8
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1107 KIAA1107
KRTAP2-4 keratin associated protein 2-4
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LSP1 lymphocyte-specific protein 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGEA5 melanoma antigen family A5
MAK male germ cell-associated kinase
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MPZ myelin protein zero
MVB12B multivesicular body subunit 12B
MYB v-myb avian myeloblastosis viral oncogene homolog
NCAN neurocan
NOVA2 neuro-oncological ventral antigen 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PER1 period circadian clock 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PHF14 PHD finger protein 14
PHF7 PHD finger protein 7
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PRDX2 peroxiredoxin 2
PXDC1 PX domain containing 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RPS3A ribosomal protein S3A
SCAND2P SCAN domain containing 2 pseudogene
SDS serine dehydratase
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SORBS3 sorbin and SH3 domain containing 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STS steroid sulfatase (microsomal), isozyme S
SYT2 synaptotagmin II
TADA2A transcriptional adaptor 2A
TFF2 trefoil factor 2
TLK1 tousled-like kinase 1
TMEM144 transmembrane protein 144
TMPRSS6 transmembrane protease, serine 6
TNXB tenascin XB
WIPF1 WAS/WASL interacting protein family, member 1
ZC3H13 zinc finger CCCH-type containing 13
ZFP37 ZFP37 zinc finger protein
ZFX zinc finger protein, X-linked
ZNF419 zinc finger protein 419
ZNF783 zinc finger family member 783
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADGRG2 adhesion G protein-coupled receptor G2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD36 ankyrin repeat domain 36
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAGE B melanoma antigen
C1QTNF3 C1q and tumor necrosis factor related protein 3
CASZ1 castor zinc finger 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CENPJ centromere protein J
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLSPN claspin
CNGB3 cyclic nucleotide gated channel beta 3
CORO1A coronin, actin binding protein, 1A
DAGLA diacylglycerol lipase, alpha
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
FAM188A family with sequence similarity 188, member A
FAM46C family with sequence similarity 46, member C
FANCE Fanconi anemia, complementation group E
FGGY FGGY carbohydrate kinase domain containing
FKBP5 FK506 binding protein 5
FSD1 fibronectin type III and SPRY domain containing 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMEB1 glucocorticoid modulatory element binding protein 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GTPBP2 GTP binding protein 2
HCRP1 hepatocellular carcinoma-related HCRP1
HIST1H2AJ histone cluster 1, H2aj
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC8 homeobox C8
HS1BP3 HCLS1 binding protein 3
HYAL2 hyaluronoglucosaminidase 2
INF2 inverted formin, FH2 and WH2 domain containing
INPP1 inositol polyphosphate-1-phosphatase
KDM7A lysine (K)-specific demethylase 7A
LARP6 La ribonucleoprotein domain family, member 6
LINC00115 long intergenic non-protein coding RNA 115
LOC100287590 uncharacterized LOC100287590
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5 low density lipoprotein receptor-related protein 5
LRRC20 leucine rich repeat containing 20
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MATK megakaryocyte-associated tyrosine kinase
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
MCOLN3 mucolipin 3
METTL16 methyltransferase like 16
MFSD11 major facilitator superfamily domain containing 11
MRPS18C mitochondrial ribosomal protein S18C
NHEJ1 nonhomologous end-joining factor 1
OSMR oncostatin M receptor
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PGPEP1 pyroglutamyl-peptidase I
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLXNA3 plexin A3
PNPLA6 patatin-like phospholipase domain containing 6
POM121 POM121 transmembrane nucleoporin
PRKX protein kinase, X-linked
PTK6 protein tyrosine kinase 6
PTPRG protein tyrosine phosphatase, receptor type, G
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB4B RAB4B, member RAS oncogene family
RANGRF RAN guanine nucleotide release factor
RPAP1 RNA polymerase II associated protein 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SAYSD1 SAYSVFN motif domain containing 1
SCPEP1 serine carboxypeptidase 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC41A3 solute carrier family 41, member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMYD5 SMYD family member 5
SP1 Sp1 transcription factor
STX1A syntaxin 1A (brain)
TBX19 T-box 19
TCTN2 tectonic family member 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TMEM104 transmembrane protein 104
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOM1 target of myb1 (chicken)
TRIM66 tripartite motif containing 66
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSSC4 tumor suppressing subtransferable candidate 4
UBXN6 UBX domain protein 6
VASH1 vasohibin 1
VAX2 ventral anterior homeobox 2
VWA1 von Willebrand factor A domain containing 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF428 zinc finger protein 428
ZSCAN26 zinc finger and SCAN domain containing 26