| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the roxarsone-5470 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTSL4 | ADAMTS-like 4 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| BCL2L1 | BCL2-like 1 |
| BIN1 | bridging integrator 1 |
| BMP2 | bone morphogenetic protein 2 |
| BPY2 | basic charge, Y-linked, 2 |
| CASD1 | CAS1 domain containing 1 |
| CCDC93 | coiled-coil domain containing 93 |
| CD300C | CD300c molecule |
| CES3 | carboxylesterase 3 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLEC11A | C-type lectin domain family 11, member A |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DFNB31 | deafness, autosomal recessive 31 |
| DST | dystonin |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ENO3 | enolase 3 (beta, muscle) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FAM120C | family with sequence similarity 120C |
| FGF9 | fibroblast growth factor 9 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GAL | galanin/GMAP prepropeptide |
| GLB1L | galactosidase, beta 1-like |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GSTA4 | glutathione S-transferase alpha 4 |
| HNMT | histamine N-methyltransferase |
| IFT140 | intraflagellar transport 140 |
| IL6ST | interleukin 6 signal transducer |
| ING1 | inhibitor of growth family, member 1 |
| KIF21B | kinesin family member 21B |
| KIF5A | kinesin family member 5A |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT17 | keratin 17, type I |
| LEFTY2 | left-right determination factor 2 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOXL2 | lysyl oxidase-like 2 |
| LRRC23 | leucine rich repeat containing 23 |
| MAGEA5 | melanoma antigen family A5 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MPO | myeloperoxidase |
| MYBPC3 | myosin binding protein C, cardiac |
| MZF1 | myeloid zinc finger 1 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NOX1 | NADPH oxidase 1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRPF31 | pre-mRNA processing factor 31 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PYGB | phosphorylase, glycogen; brain |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBBP4 | retinoblastoma binding protein 4 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPH3A | rabphilin 3A |
| RPS6 | ribosomal protein S6 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RUNDC3A | RUN domain containing 3A |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SIRT3 | sirtuin 3 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SP1 | Sp1 transcription factor |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SRRT | serrate, RNA effector molecule |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAOK2 | TAO kinase 2 |
| TBC1D2B | TBC1 domain family, member 2B |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TNPO2 | transportin 2 |
| TRIM25 | tripartite motif containing 25 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WDR76 | WD repeat domain 76 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WTAP | Wilms tumor 1 associated protein |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF318 | zinc finger protein 318 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATG7 | autophagy related 7 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BTBD2 | BTB (POZ) domain containing 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| CBX4 | chromobox homolog 4 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNL2 | cyclin L2 |
| CD302 | CD302 molecule |
| CDKN2AIP | CDKN2A interacting protein |
| CENPO | centromere protein O |
| CEP170B | centrosomal protein 170B |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CISH | cytokine inducible SH2-containing protein |
| CLASRP | CLK4-associating serine/arginine rich protein |
| CLDN9 | claudin 9 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ENO2 | enolase 2 (gamma, neuronal) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM186A | family with sequence similarity 186, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXO31 | F-box protein 31 |
| GAS8 | growth arrest-specific 8 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HMOX1 | heme oxygenase 1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| INO80D | INO80 complex subunit D |
| IRF6 | interferon regulatory factor 6 |
| JMJD4 | jumonji domain containing 4 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0556 | KIAA0556 |
| KLC2 | kinesin light chain 2 |
| KLF2 | Kruppel-like factor 2 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MANBA | mannosidase, beta A, lysosomal |
| MOSPD3 | motile sperm domain containing 3 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PC | pyruvate carboxylase |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| POMZP3 | POM121 and ZP3 fusion |
| POPDC3 | popeye domain containing 3 |
| PRSS8 | protease, serine, 8 |
| PSKH1 | protein serine kinase H1 |
| PTK6 | protein tyrosine kinase 6 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASA2 | RAS p21 protein activator 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF43 | ring finger protein 43 |
| SCAI | suppressor of cancer cell invasion |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SETMAR | SET domain and mariner transposase fusion gene |
| SH2B3 | SH2B adaptor protein 3 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SPHK1 | sphingosine kinase 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SREK1IP1 | SREK1-interacting protein 1 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM57 | transmembrane protein 57 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR19 | WD repeat domain 19 |
| XYLT2 | xylosyltransferase II |
| ZNF574 | zinc finger protein 574 |
| ZNF586 | zinc finger protein 586 |
| ZNF639 | zinc finger protein 639 |
| ZNF701 | zinc finger protein 701 |