roxithromycin-2992 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the roxithromycin-2992 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH6 alcohol dehydrogenase 6 (class V)
ADIRF adipogenesis regulatory factor
ANG angiogenin, ribonuclease, RNase A family, 5
ANK2 ankyrin 2, neuronal
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
AQP7 aquaporin 7
BDNF brain-derived neurotrophic factor
BPY2 basic charge, Y-linked, 2
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C9ORF9 chromosome 9 open reading frame 9
CASZ1 castor zinc finger 1
CD160 CD160 molecule
CDC25C cell division cycle 25C
CLIP2 CAP-GLY domain containing linker protein 2
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CSPG4 chondroitin sulfate proteoglycan 4
CTC1 CTS telomere maintenance complex component 1
CYHR1 cysteine/histidine-rich 1
DMC1 DNA meiotic recombinase 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DST dystonin
EDN3 endothelin 3
EFS embryonal Fyn-associated substrate
EHD2 EH-domain containing 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FDPS farnesyl diphosphate synthase
FLRT2 fibronectin leucine rich transmembrane protein 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFER growth factor, augmenter of liver regeneration
GP9 glycoprotein IX (platelet)
GPR22 G protein-coupled receptor 22
GSTA1 glutathione S-transferase alpha 1
GSTT1 glutathione S-transferase theta 1
GUCA2B guanylate cyclase activator 2B (uroguanylin)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2BG histone cluster 1, H2bg
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL36RN interleukin 36 receptor antagonist
INCENP inner centromere protein antigens 135/155kDa
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KLC2 kinesin light chain 2
KLK3 kallikrein-related peptidase 3
LAMB2 laminin, beta 2 (laminin S)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMD2 LIM domain containing 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC730101 uncharacterized LOC730101
LOX lysyl oxidase
MIR22HG MIR22 host gene
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYLK myosin light chain kinase
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEU3 sialidase 3 (membrane sialidase)
NFIB nuclear factor I/B
NRP1 neuropilin 1
OCM2 oncomodulin 2
PAGE4 P antigen family, member 4 (prostate associated)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POMT2 protein-O-mannosyltransferase 2
PPY pancreatic polypeptide
PRB4 proline-rich protein BstNI subfamily 4
PRKG2 protein kinase, cGMP-dependent, type II
PROS1 protein S (alpha)
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVR poliovirus receptor
RELN reelin
RERE arginine-glutamic acid dipeptide (RE) repeats
RHAG Rh-associated glycoprotein
RPL10 ribosomal protein L10
RPL23AP53 ribosomal protein L23a pseudogene 53
SCN11A sodium channel, voltage gated, type XI alpha subunit
SERHL2 serine hydrolase-like 2
SFTPA2 surfactant protein A2
SH2D3A SH2 domain containing 3A
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC12A8 solute carrier family 12, member 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SORT1 sortilin 1
SRPK3 SRSF protein kinase 3
SSTR4 somatostatin receptor 4
STS steroid sulfatase (microsomal), isozyme S
SVIL supervillin
SYCE1L synaptonemal complex central element protein 1-like
TNPO2 transportin 2
TPM3 tropomyosin 3
TUBA4B tubulin, alpha 4b
USP53 ubiquitin specific peptidase 53
XCL1 chemokine (C motif) ligand 1
XIST X inactive specific transcript (non-protein coding)
ZNF442 zinc finger protein 442
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANKRD40 ankyrin repeat domain 40
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARRB1 arrestin, beta 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTF3P11 basic transcription factor 3 pseudogene 11
C3ORF18 chromosome 3 open reading frame 18
C5AR1 complement component 5a receptor 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CD37 CD37 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDR2L cerebellar degeneration-related protein 2-like
CECR1 cat eye syndrome chromosome region, candidate 1
CEP131 centrosomal protein 131kDa
CHMP1A charged multivesicular body protein 1A
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPTP ceramide-1-phosphate transfer protein
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DOK2 docking protein 2, 56kDa
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FANCC Fanconi anemia, complementation group C
FBXL7 F-box and leucine-rich repeat protein 7
FMO4 flavin containing monooxygenase 4
FRMPD1 FERM and PDZ domain containing 1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GBP2 guanylate binding protein 2, interferon-inducible
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
GSDMD gasdermin D
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HHLA3 HERV-H LTR-associating 3
HIST1H1E histone cluster 1, H1e
HPR haptoglobin-related protein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ISG15 ISG15 ubiquitin-like modifier
KIAA0753 KIAA0753
KLHL26 kelch-like family member 26
LIME1 Lck interacting transmembrane adaptor 1
LINC00260 long intergenic non-protein coding RNA 260
LPPR1 lipid phosphate phosphatase-related protein type 1
LTC4S leukotriene C4 synthase
LZTR1 leucine-zipper-like transcription regulator 1
MAGEH1 melanoma antigen family H1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBL1P mannose-binding lectin (protein A) 1, pseudogene
METTL21B methyltransferase like 21B
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCKAP1L NCK-associated protein 1-like
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NINJ2 ninjurin 2
NME8 NME/NM23 family member 8
NOL12 nucleolar protein 12
NT5C 5', 3'-nucleotidase, cytosolic
OCLN occludin
PARP16 poly (ADP-ribose) polymerase family, member 16
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIP prolactin-induced protein
PLA2G12A phospholipase A2, group XIIA
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POR P450 (cytochrome) oxidoreductase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTDSS2 phosphatidylserine synthase 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD1A SET domain containing 1A
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIDT1 SID1 transmembrane family, member 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC16A4 solute carrier family 16, member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F6 solute carrier family 35, member F6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMYD5 SMYD family member 5
SPATA2L spermatogenesis associated 2-like
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STAT5A signal transducer and activator of transcription 5A
TBX19 T-box 19
TESPA1 thymocyte expressed, positive selection associated 1
TMEM180 transmembrane protein 180
TOM1 target of myb1 (chicken)
TRPC5 transient receptor potential cation channel, subfamily C, member 5
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WT1-AS WT1 antisense RNA
ZBED8 zinc finger, BED-type containing 8
ZC3H3 zinc finger CCCH-type containing 3
ZFHX3 zinc finger homeobox 3
ZNF177 zinc finger protein 177
ZNF37BP zinc finger protein 37B, pseudogene