| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the roxithromycin-3331 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AHSP | alpha hemoglobin stabilizing protein |
| AIM1L | absent in melanoma 1-like |
| AJAP1 | adherens junctions associated protein 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK6 | cyclin-dependent kinase 6 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CLCA1 | chloride channel accessory 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CTSF | cathepsin F |
| DLG1 | discs, large homolog 1 (Drosophila) |
| DRD1 | dopamine receptor D1 |
| DSC3 | desmocollin 3 |
| DST | dystonin |
| DUSP6 | dual specificity phosphatase 6 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| FGF5 | fibroblast growth factor 5 |
| FMO5 | flavin containing monooxygenase 5 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FZD10 | frizzled class receptor 10 |
| FZD5 | frizzled class receptor 5 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| HOXA10 | homeobox A10 |
| HOXA9 | homeobox A9 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL2 | interleukin 2 |
| IL2RG | interleukin 2 receptor, gamma |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KDM4B | lysine (K)-specific demethylase 4B |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA1024 | KIAA1024 |
| KIF1C | kinesin family member 1C |
| KRT83 | keratin 83, type II |
| KXD1 | KxDL motif containing 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MUC3B | mucin 3B, cell surface associated |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NME5 | NME/NM23 family member 5 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NTF3 | neurotrophin 3 |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PEX5 | peroxisomal biogenesis factor 5 |
| PLAT | plasminogen activator, tissue |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POU3F4 | POU class 3 homeobox 4 |
| PSAT1 | phosphoserine aminotransferase 1 |
| RAB6B | RAB6B, member RAS oncogene family |
| REC8 | REC8 meiotic recombination protein |
| SAMD9 | sterile alpha motif domain containing 9 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STAB1 | stabilin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYMPK | symplekin |
| SYT11 | synaptotagmin XI |
| TCF3 | transcription factor 3 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TPMT | thiopurine S-methyltransferase |
| TRIM31 | tripartite motif containing 31 |
| TSC22D2 | TSC22 domain family, member 2 |
| UBXN1 | UBX domain protein 1 |
| XCR1 | chemokine (C motif) receptor 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF236 | zinc finger protein 236 |
| ZNF440 | zinc finger protein 440 |
| ZNF646 | zinc finger protein 646 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALS2CL | ALS2 C-terminal like |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BAK1 | BCL2-antagonist/killer 1 |
| BBC3 | BCL2 binding component 3 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLDND1 | claudin domain containing 1 |
| CLK1 | CDC-like kinase 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRY2 | cryptochrome circadian clock 2 |
| CSTA | cystatin A (stefin A) |
| CTAGE9 | CTAGE family, member 9 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIXDC1 | DIX domain containing 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| F2R | coagulation factor II (thrombin) receptor |
| FGL1 | fibrinogen-like 1 |
| FOCAD | focadhesin |
| GAMT | guanidinoacetate N-methyltransferase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR157 | G protein-coupled receptor 157 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H2AFY2 | H2A histone family, member Y2 |
| HIRA | histone cell cycle regulator |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF6 | interferon regulatory factor 6 |
| JUNB | jun B proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0754 | KIAA0754 |
| KLF2 | Kruppel-like factor 2 |
| KLHL25 | kelch-like family member 25 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MCC | mutated in colorectal cancers |
| METTL2B | methyltransferase like 2B |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MTMR6 | myotubularin related protein 6 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDHA9 | protocadherin alpha 9 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBL1 | retinoblastoma-like 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RWDD3 | RWD domain containing 3 |
| SCHIP1 | schwannomin interacting protein 1 |
| SDC3 | syndecan 3 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STK4 | serine/threonine kinase 4 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLR5 | toll-like receptor 5 |
| TMEM209 | transmembrane protein 209 |
| TMEM254 | transmembrane protein 254 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TUBA3C | tubulin, alpha 3c |
| WDR33 | WD repeat domain 33 |
| WDR4 | WD repeat domain 4 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF16 | zinc finger protein 16 |
| ZNF227 | zinc finger protein 227 |
| ZNF35 | zinc finger protein 35 |
| ZNF446 | zinc finger protein 446 |
| ZNF480 | zinc finger protein 480 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF665 | zinc finger protein 665 |
