| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the roxithromycin-4192 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADAM7 | ADAM metallopeptidase domain 7 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ATF7IP | activating transcription factor 7 interacting protein |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CACNG5 | calcium channel, voltage-dependent, gamma subunit 5 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC1A | C-type lectin domain family 1, member A |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CORO2B | coronin, actin binding protein, 2B |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRISP2 | cysteine-rich secretory protein 2 |
| DAPK2 | death-associated protein kinase 2 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DOK4 | docking protein 4 |
| DPYS | dihydropyrimidinase |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EFS | embryonal Fyn-associated substrate |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FAM120C | family with sequence similarity 120C |
| FBXO41 | F-box protein 41 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GLRA1 | glycine receptor, alpha 1 |
| GPATCH4 | G patch domain containing 4 |
| GPC3 | glypican 3 |
| GPR27 | G protein-coupled receptor 27 |
| GPSM3 | G-protein signaling modulator 3 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GZMM | granzyme M (lymphocyte met-ase 1) |
| H2AFX | H2A histone family, member X |
| HABP2 | hyaluronan binding protein 2 |
| HIC2 | hypermethylated in cancer 2 |
| HPSE2 | heparanase 2 (inactive) |
| IL1R1 | interleukin 1 receptor, type I |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| IZUMO4 | IZUMO family member 4 |
| KIF1C | kinesin family member 1C |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LILRP2 | leukocyte immunoglobulin-like receptor pseudogene 2 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAPT | microtubule-associated protein tau |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMRN2 | multimerin 2 |
| MPPE1 | metallophosphoesterase 1 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NPTX1 | neuronal pentraxin I |
| NPTXR | neuronal pentraxin receptor |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OGDHL | oxoglutarate dehydrogenase-like |
| OGFR | opioid growth factor receptor |
| PADI4 | peptidyl arginine deiminase, type IV |
| PCDHA5 | protocadherin alpha 5 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIK3C2G | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLVAP | plasmalemma vesicle associated protein |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKCA | protein kinase C, alpha |
| PRMT2IP | PRMT2 interacting protein |
| RARA | retinoic acid receptor, alpha |
| RBFA | ribosome binding factor A (putative) |
| REG1A | regenerating islet-derived 1 alpha |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RGR | retinal G protein coupled receptor |
| RGS16 | regulator of G-protein signaling 16 |
| RHO | rhodopsin |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPL35A | ribosomal protein L35a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| TBC1D30 | TBC1 domain family, member 30 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TP73-AS1 | TP73 antisense RNA 1 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTC12 | tetratricopeptide repeat domain 12 |
| WISP3 | WNT1 inducible signaling pathway protein 3 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF688 | zinc finger protein 688 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5 | complement component 5 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK3 | cyclin-dependent kinase 3 |
| CEMP1 | cementum protein 1 |
| CLSPN | claspin |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| EBF2 | early B-cell factor 2 |
| ERCC5 | excision repair cross-complementation group 5 |
| EXOC6B | exocyst complex component 6B |
| GALK1 | galactokinase 1 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GAS8 | growth arrest-specific 8 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPX2 | glutathione peroxidase 2 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA6 | homeobox A6 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KRT86 | keratin 86, type II |
| LMNB1 | lamin B1 |
| LMTK1 | lemur tail kinase 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC61 | leucine rich repeat containing 61 |
| LY86 | lymphocyte antigen 86 |
| MAGEA6 | melanoma antigen family A6 |
| MANBA | mannosidase, beta A, lysosomal |
| MAPK12 | mitogen-activated protein kinase 12 |
| MMP2 | matrix metallopeptidase 2 |
| MRAS | muscle RAS oncogene homolog |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTRF1 | mitochondrial translational release factor 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NBEAL2 | neurobeachin-like 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OTOF | otoferlin |
| PCDH12 | protocadherin 12 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PMCH | pro-melanin-concentrating hormone |
| PRF1 | perforin 1 (pore forming protein) |
| PROX1 | prospero homeobox 1 |
| PRR15L | proline rich 15-like |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS53 | protease, serine, 53 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RIN1 | Ras and Rab interactor 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RRAGB | Ras-related GTP binding B |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SETD1A | SET domain containing 1A |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SPRYD7 | SPRY domain containing 7 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STRN | striatin, calmodulin binding protein |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBKBP1 | TBK1 binding protein 1 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM2 | transmembrane protein 2 |
| TUBA3C | tubulin, alpha 3c |
| VASH1 | vasohibin 1 |
| VGF | VGF nerve growth factor inducible |
| VGLL3 | vestigial-like family member 3 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF215 | zinc finger protein 215 |
| ZNF253 | zinc finger protein 253 |
| ZNF385D | zinc finger protein 385D |
| ZNF557 | zinc finger protein 557 |
| ZNF747 | zinc finger protein 747 |
| ZNF816 | zinc finger protein 816 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
