| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the roxithromycin-4778 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGB | androglobin |
| AFAP1 | actin filament associated protein 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMACR | alpha-methylacyl-CoA racemase |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| AREG | amphiregulin |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BTN3A3 | butyrophilin, subfamily 3, member A3 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C4BPA | complement component 4 binding protein, alpha |
| CA12 | carbonic anhydrase XII |
| CABP1 | calcium binding protein 1 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC33 | coiled-coil domain containing 33 |
| CCDC57 | coiled-coil domain containing 57 |
| CD28 | CD28 molecule |
| CD4 | CD4 molecule |
| CDHR5 | cadherin-related family member 5 |
| CHKB | choline kinase beta |
| CLIC2 | chloride intracellular channel 2 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL5A2 | collagen, type V, alpha 2 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EMID1 | EMI domain containing 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHA1 | EPH receptor A1 |
| EPOR | erythropoietin receptor |
| FGF6 | fibroblast growth factor 6 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAB1 | GRB2-associated binding protein 1 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HOXA4 | homeobox A4 |
| KANK3 | KN motif and ankyrin repeat domains 3 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIAA0226L | KIAA0226-like |
| KNG1 | kininogen 1 |
| KRT16 | keratin 16, type I |
| KRT20 | keratin 20, type I |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| MALL | mal, T-cell differentiation protein-like |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MEF2D | myocyte enhancer factor 2D |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MPO | myeloperoxidase |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NCOA2 | nuclear receptor coactivator 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCDHA5 | protocadherin alpha 5 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRDM9 | PR domain containing 9 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTN | pleiotrophin |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RAB11B | RAB11B, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RND2 | Rho family GTPase 2 |
| SGSM3 | small G protein signaling modulator 3 |
| SIRT5 | sirtuin 5 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC26A1 | solute carrier family 26 (anion exchanger), member 1 |
| SLC35G2 | solute carrier family 35, member G2 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STOML1 | stomatin (EPB72)-like 1 |
| SYCE1L | synaptonemal complex central element protein 1-like |
| TCP10 | t-complex 10 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM2 | tripartite motif containing 2 |
| TROVE2 | TROVE domain family, member 2 |
| VARS | valyl-tRNA synthetase |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WDR78 | WD repeat domain 78 |
| WSCD1 | WSC domain containing 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZNF204P | zinc finger protein 204, pseudogene |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACO1 | aconitase 1, soluble |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| AGO3 | argonaute RISC catalytic component 3 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| BAGE | B melanoma antigen |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| CCDC88C | coiled-coil domain containing 88C |
| CCDC91 | coiled-coil domain containing 91 |
| CEP72 | centrosomal protein 72kDa |
| CHEK2 | checkpoint kinase 2 |
| CLK1 | CDC-like kinase 1 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CPOX | coproporphyrinogen oxidase |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHA4 | EPH receptor A4 |
| ERBB2IP | erbb2 interacting protein |
| ERCC8 | excision repair cross-complementation group 8 |
| FAM169A | family with sequence similarity 169, member A |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BI | histone cluster 1, H2bi |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IRF6 | interferon regulatory factor 6 |
| KIF20B | kinesin family member 20B |
| KLF11 | Kruppel-like factor 11 |
| KLHL21 | kelch-like family member 21 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LPXN | leupaxin |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MANBA | mannosidase, beta A, lysosomal |
| MED23 | mediator complex subunit 23 |
| MED4 | mediator complex subunit 4 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| NEK11 | NIMA-related kinase 11 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD3 | phospholipase D family, member 3 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PRSS22 | protease, serine, 22 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RNFT2 | ring finger protein, transmembrane 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SCAI | suppressor of cancer cell invasion |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNIP1 | Smad nuclear interacting protein 1 |
| SNX16 | sorting nexin 16 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STX1A | syntaxin 1A (brain) |
| TAOK1 | TAO kinase 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCERG1 | transcription elongation regulator 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPAN15 | tetraspanin 15 |
| UBXN6 | UBX domain protein 6 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR19 | WD repeat domain 19 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF273 | zinc finger protein 273 |
| ZNF302 | zinc finger protein 302 |
| ZNF329 | zinc finger protein 329 |
| ZNF408 | zinc finger protein 408 |
| ZNF428 | zinc finger protein 428 |
| ZNF430 | zinc finger protein 430 |
| ZNF652 | zinc finger protein 652 |
| ZNF696 | zinc finger protein 696 |
| ZNF74 | zinc finger protein 74 |
| ZNF770 | zinc finger protein 770 |
| ZNF816 | zinc finger protein 816 |
| ZNF83 | zinc finger protein 83 |
