rpa Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa. (Gene Ontology, GO_0005662)
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Genes

56 genes co-occuring with the biological term rpa in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATR ATR serine/threonine kinase
BID BH3 interacting domain death agonist
BLM Bloom syndrome, RecQ helicase-like
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
CETN2 centrin, EF-hand protein, 2
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
FAN1 FANCD2/FANCI-associated nuclease 1
FANCM Fanconi anemia, complementation group M
H2AFX H2A histone family, member X
HELB helicase (DNA) B
HLTF helicase-like transcription factor
HMGB1 high mobility group box 1
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
IFI16 interferon, gamma-inducible protein 16
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
MCM6 minichromosome maintenance complex component 6
MEIOB meiosis specific with OB domains
MLH1 mutL homolog 1
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NABP2 nucleic acid binding protein 2
NBN nibrin
NEIL1 nei endonuclease VIII-like 1 (E. coli)
PCNA proliferating cell nuclear antigen
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLB polymerase (DNA directed), beta
POLQ polymerase (DNA directed), theta
POT1 protection of telomeres 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF19 pre-mRNA processing factor 19
RAD17 RAD17 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RFC2 replication factor C (activator 1) 2, 40kDa
RLBP1 retinaldehyde binding protein 1
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA4 replication protein A4, 30kDa
RPAIN RPA interacting protein
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
TIMELESS timeless circadian clock
TIPIN TIMELESS interacting protein
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
UNG uracil-DNA glycosylase
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C