| Dataset | GO Biological Process Annotations 2025 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. (Gene Ontology, GO_0097178) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0097178 |
| Similar Terms | |
| Downloads & Tools |
6 genes participating in the ruffle assembly biological process from the curated GO Biological Process Annotations 2025 dataset.
