s100a4 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description S100 calcium binding protein A4|The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6275)
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Genes

77 genes co-occuring with the biological term s100a4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
AGR2 anterior gradient 2
ANXA2 annexin A2
BCL2 B-cell CLL/lymphoma 2
BMP2 bone morphogenetic protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPG capping protein (actin filament), gelsolin-like
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC4 chloride intracellular channel 4
CXCR4 chemokine (C-X-C motif) receptor 4
ENG endoglin
ERBB2 erb-b2 receptor tyrosine kinase 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FST follistatin
GPR39 G protein-coupled receptor 39
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IDO1 indoleamine 2,3-dioxygenase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL10 interleukin 10
IL1B interleukin 1, beta
IL7 interleukin 7
INSL3 insulin-like 3 (Leydig cell)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
JAK3 Janus kinase 3
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METAP2 methionyl aminopeptidase 2
MIR155 microRNA 155
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MYB v-myb avian myeloblastosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-2 NK2 homeobox 2
NOTCH1 notch 1
PDLIM4 PDZ and LIM domain 4
PGLYRP1 peptidoglycan recognition protein 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PROM1 prominin 1
RLN1 relaxin 1
RPS12 ribosomal protein S12
RTKN rhotekin
S100A1 S100 calcium binding protein A1
S100A11 S100 calcium binding protein A11
S100A12 S100 calcium binding protein A12
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
S100P S100 calcium binding protein P
SAA1 serum amyloid A1
SAA3P serum amyloid A3 pseudogene
SDC1 syndecan 1
SMAD3 SMAD family member 3
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRXN1 sulfiredoxin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
VEGFA vascular endothelial growth factor A
ZEB1 zinc finger E-box binding homeobox 1