s100a6 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description S100 calcium binding protein A6|The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6277)
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Genes

23 genes co-occuring with the biological term s100a6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ANXA2 annexin A2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
EP300 E1A binding protein p300
LMNA lamin A/C
MAPK1 mitogen-activated protein kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP9 matrix metallopeptidase 9
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
S100A1 S100 calcium binding protein A1
S100A10 S100 calcium binding protein A10
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
S100B S100 calcium binding protein B
S100P S100 calcium binding protein P
SP1 Sp1 transcription factor
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
TNF tumor necrosis factor
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TP53 tumor protein p53
USF1 upstream transcription factor 1