s100a8 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description S100 calcium binding protein A8|The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6279)
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Genes

29 genes co-occuring with the biological term s100a8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HLA-B major histocompatibility complex, class I, B
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL4 interleukin 4
IL6 interleukin 6
KRT1 keratin 1, type II
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP3 NLR family, pyrin domain containing 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SMAD4 SMAD family member 4
SOD2 superoxide dismutase 2, mitochondrial
TERT telomerase reverse transcriptase
TLR4 toll-like receptor 4
TNF tumor necrosis factor
UBE2C ubiquitin-conjugating enzyme E2C