saccharin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent. (Chemical Entities of Biological Interest Ontology, CHEBI_32111)
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Genes

4 genes differentially expressed following the saccharin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 6.26603
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.61653

decreased expression

Symbol Name Standardized Value
SIRT3 sirtuin 3 -3.95806
C2CD2 C2 calcium-dependent domain containing 2 -3.01053