saga complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery. (Gene Ontology, GO_0000124)
Similar Terms
Downloads & Tools

Genes

94 proteins co-occuring with the saga complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CCDC101 coiled-coil domain containing 101 1.89316
ATXN7 ataxin 7 1.38905
HIST1H2BD histone cluster 1, H2bd 1.37851
HIST1H2BH histone cluster 1, H2bh 1.37851
HIST3H2BB histone cluster 3, H2bb 1.37851
HIST2H2BF histone cluster 2, H2bf 1.37851
HIST1H2BF histone cluster 1, H2bf 1.3763
HIST1H2BC histone cluster 1, H2bc 1.3763
HIST1H2BA histone cluster 1, H2ba 1.37464
ATXN7L3 ataxin 7-like 3 1.3532
USP22 ubiquitin specific peptidase 22 1.32167
TADA2A transcriptional adaptor 2A 1.26339
TADA3 transcriptional adaptor 3 1.18646
TADA2B transcriptional adaptor 2B 1.14546
TAF8 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa 1.14187
KAT2B K(lysine) acetyltransferase 2B 1.0873
TREX2 three prime repair exonuclease 2 1.06195
TRRAP transformation/transcription domain-associated protein 1.05438
TBP TATA box binding protein 0.995632
ENY2 enhancer of yellow 2 homolog (Drosophila) 0.936432
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.906926
H3F3A H3 histone, family 3A 0.902745
H3F3B H3 histone, family 3B (H3.3B) 0.902745
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.873647
KAT2A K(lysine) acetyltransferase 2A 0.849746
ZNF569 zinc finger protein 569 0.835974
ZNF763 zinc finger protein 763 0.835974
ZNF501 zinc finger protein 501 0.835974
ZNF629 zinc finger protein 629 0.835974
ZNF44 zinc finger protein 44 0.83322
BCL6B B-cell CLL/lymphoma 6, member B 0.826794
ZNF436 zinc finger protein 436 0.8089
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.782326
GLYATL1 glycine-N-acyltransferase-like 1 0.757253
LGALS1 lectin, galactoside-binding, soluble, 1 0.749999
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.748189
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.71768
GTF2B general transcription factor IIB 0.716791
ZKSCAN7 zinc finger with KRAB and SCAN domains 7 0.707039
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.63715
SNRPA1 small nuclear ribonucleoprotein polypeptide A' 0.629039
ZNF135 zinc finger protein 135 0.62393
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.598117
SLK STE20-like kinase 0.571745
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.537005
MED26 mediator complex subunit 26 0.502288
BCL6 B-cell CLL/lymphoma 6 0.488115
TCF3 transcription factor 3 0.480855
LRWD1 leucine-rich repeats and WD repeat domain containing 1 0.476429
TCF12 transcription factor 12 0.436565
APTX aprataxin 0.422389
LGALS7B lectin, galactoside-binding, soluble, 7B 0.421212
RPS5 ribosomal protein S5 0.403248
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.388523
HIST1H4F histone cluster 1, H4f 0.364713
HIST2H4A histone cluster 2, H4a 0.364713
HIST1H4H histone cluster 1, H4h 0.364713
HIST2H4B histone cluster 2, H4b 0.364713
HIST1H4I histone cluster 1, H4i 0.364713
HIST1H4E histone cluster 1, H4e 0.364713
HIST1H4D histone cluster 1, H4d 0.364713
HIST1H4A histone cluster 1, H4a 0.364713
HIST1H4K histone cluster 1, H4k 0.364713
HIST1H4B histone cluster 1, H4b 0.364713
HIST1H4C histone cluster 1, H4c 0.364713
HIST1H4J histone cluster 1, H4j 0.364713
HIST1H4L histone cluster 1, H4l 0.364331
HIST4H4 histone cluster 4, H4 0.364331
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.343799
MARCKSL1 MARCKS-like 1 0.341907
NBPF1 neuroblastoma breakpoint family, member 1 0.332472
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.320451
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.320077
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.309986
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.301054
CNOT1 CCR4-NOT transcription complex, subunit 1 0.289938
LSM1 LSM1, U6 small nuclear RNA associated 0.274468
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.271167
ISYNA1 inositol-3-phosphate synthase 1 0.251476
PNN pinin, desmosome associated protein 0.250026
PBX1 pre-B-cell leukemia homeobox 1 0.235249
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.218914
EIF6 eukaryotic translation initiation factor 6 0.197993
PPP6C protein phosphatase 6, catalytic subunit 0.188905
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 0.18859
PPP5C protein phosphatase 5, catalytic subunit 0.184241
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.183328
CHD1 chromodomain helicase DNA binding protein 1 0.179752
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.170114
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.168847
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.16298
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.161484
AGPS alkylglycerone phosphate synthase 0.160863
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 0.156863