saga complex Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery. (Gene Ontology, GO_0000124)
External Link http://amigo.geneontology.org/amigo/term/GO:0000124
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Genes

7 proteins localized to the saga complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
ATXN7L3 ataxin 7-like 3
ENY2 enhancer of yellow 2 homolog (Drosophila)
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
USP22 ubiquitin specific peptidase 22
USP51 ubiquitin specific peptidase 51