salsolidin-2824 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the salsolidin-2824 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRA1D adrenoceptor alpha 1D
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APLP2 amyloid beta (A4) precursor-like protein 2
AR androgen receptor
ATM ATM serine/threonine kinase
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAIAP2 BAI1-associated protein 2
BMP8B bone morphogenetic protein 8b
BTN3A1 butyrophilin, subfamily 3, member A1
C11ORF63 chromosome 11 open reading frame 63
C4ORF29 chromosome 4 open reading frame 29
C8ORF60 chromosome 8 open reading frame 60
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CCDC9 coiled-coil domain containing 9
CD82 CD82 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM188A family with sequence similarity 188, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FMO4 flavin containing monooxygenase 4
FYN FYN proto-oncogene, Src family tyrosine kinase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HEXA hexosaminidase A (alpha polypeptide)
HFE hemochromatosis
HIST1H4E histone cluster 1, H4e
HSDL2 hydroxysteroid dehydrogenase like 2
IDS iduronate 2-sulfatase
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00341 long intergenic non-protein coding RNA 341
LTBP2 latent transforming growth factor beta binding protein 2
LTBP4 latent transforming growth factor beta binding protein 4
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAOB monoamine oxidase B
MAPK10 mitogen-activated protein kinase 10
MAPK8 mitogen-activated protein kinase 8
MASP2 mannan-binding lectin serine peptidase 2
MCC mutated in colorectal cancers
MED18 mediator complex subunit 18
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MINK1 misshapen-like kinase 1
MITF microphthalmia-associated transcription factor
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYO1B myosin IB
NAAA N-acylethanolamine acid amidase
NOD1 nucleotide-binding oligomerization domain containing 1
NOV nephroblastoma overexpressed
PARD6B par-6 family cell polarity regulator beta
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCL2 phospholipase C-like 2
POM121 POM121 transmembrane nucleoporin
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRB4 proline-rich protein BstNI subfamily 4
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PVR poliovirus receptor
QKI QKI, KH domain containing, RNA binding
RABGAP1 RAB GTPase activating protein 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM19 RNA binding motif protein 19
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNFT1 ring finger protein, transmembrane 1
RPL18 ribosomal protein L18
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SCN11A sodium channel, voltage gated, type XI alpha subunit
SFRP4 secreted frizzled-related protein 4
SGK2 serum/glucocorticoid regulated kinase 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SORBS3 sorbin and SH3 domain containing 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBL1Y transducin (beta)-like 1, Y-linked
TMEM53 transmembrane protein 53
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TRAK1 trafficking protein, kinesin binding 1
TRIM16 tripartite motif containing 16
TULP2 tubby like protein 2
USP34 ubiquitin specific peptidase 34
USP36 ubiquitin specific peptidase 36
WDR76 WD repeat domain 76
ZFP64 ZFP64 zinc finger protein
ZMYND8 zinc finger, MYND-type containing 8
ZNF286A zinc finger protein 286A
ZNF419 zinc finger protein 419
ZNF518A zinc finger protein 518A
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ADGRA3 adhesion G protein-coupled receptor A3
ANKRD40 ankyrin repeat domain 40
ASAP1-IT1 ASAP1 intronic transcript 1
ATG9A autophagy related 9A
AXIN1 axin 1
BAGE B melanoma antigen
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
C16ORF45 chromosome 16 open reading frame 45
C1ORF115 chromosome 1 open reading frame 115
C7ORF43 chromosome 7 open reading frame 43
CABIN1 calcineurin binding protein 1
CEP170B centrosomal protein 170B
CHPF chondroitin polymerizing factor
CHRM3 cholinergic receptor, muscarinic 3
CLDN15 claudin 15
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLUH clustered mitochondria (cluA/CLU1) homolog
CORO2A coronin, actin binding protein, 2A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CXORF56 chromosome X open reading frame 56
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
DVL1 dishevelled segment polarity protein 1
EPN3 epsin 3
F2R coagulation factor II (thrombin) receptor
FAM46C family with sequence similarity 46, member C
FOXO1 forkhead box O1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS2 fibroblast growth factor receptor substrate 2
GID4 GID complex subunit 4
GLI3 GLI family zinc finger 3
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC4 histone deacetylase 4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
ICK intestinal cell (MAK-like) kinase
IDI2-AS1 IDI2 antisense RNA 1
IFI35 interferon-induced protein 35
IFT140 intraflagellar transport 140
IQCE IQ motif containing E
IRF2 interferon regulatory factor 2
IRX4 iroquois homeobox 4
KIAA0319L KIAA0319-like
KLC2 kinesin light chain 2
MAST3 microtubule associated serine/threonine kinase 3
MT1H metallothionein 1H
MTMR6 myotubularin related protein 6
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NCS1 neuronal calcium sensor 1
NPTX1 neuronal pentraxin I
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ORAI3 ORAI calcium release-activated calcium modulator 3
OTUD3 OTU deubiquitinase 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCDHB8 protocadherin beta 8
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLA2G3 phospholipase A2, group III
PLEC plectin
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLH polymerase (DNA directed), eta
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRKX protein kinase, X-linked
RAB5C RAB5C, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RNF31 ring finger protein 31
SCAMP4 secretory carrier membrane protein 4
SFT2D2 SFT2 domain containing 2
SFXN1 sideroflexin 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SND1-IT1 SND1 intronic transcript 1
SRPX sushi-repeat containing protein, X-linked
SSBP3 single stranded DNA binding protein 3
STARD3 StAR-related lipid transfer (START) domain containing 3
TARP TCR gamma alternate reading frame protein
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TRABD TraB domain containing
TRAIP TRAF interacting protein
TTC30A tetratricopeptide repeat domain 30A
TTLL1 tubulin tyrosine ligase-like family member 1
TWF2 twinfilin actin binding protein 2
ULBP2 UL16 binding protein 2
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
VASP vasodilator-stimulated phosphoprotein
WDR25 WD repeat domain 25
XK X-linked Kx blood group
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YBX2 Y box binding protein 2
YY2 YY2 transcription factor
ZFHX3 zinc finger homeobox 3
ZNF212 zinc finger protein 212
ZNF552 zinc finger protein 552
ZNF571 zinc finger protein 571