salsolinol-4232 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the salsolinol-4232 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALDOB aldolase B, fructose-bisphosphate
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOH apolipoprotein H (beta-2-glycoprotein I)
ARL14 ADP-ribosylation factor-like 14
BMP7 bone morphogenetic protein 7
BTF3P11 basic transcription factor 3 pseudogene 11
C1S complement component 1, s subcomponent
CABP1 calcium binding protein 1
CAPN9 calpain 9
CASC1 cancer susceptibility candidate 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDK13 cyclin-dependent kinase 13
CDK20 cyclin-dependent kinase 20
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CEP164 centrosomal protein 164kDa
CLEC1A C-type lectin domain family 1, member A
COL3A1 collagen, type III, alpha 1
COL4A6 collagen, type IV, alpha 6
CRHR2 corticotropin releasing hormone receptor 2
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
ERGIC3 ERGIC and golgi 3
EVI2B ecotropic viral integration site 2B
FCAR Fc fragment of IgA receptor
GAP43 growth associated protein 43
GJD2 gap junction protein, delta 2, 36kDa
GPC3 glypican 3
GRM7 glutamate receptor, metabotropic 7
HABP4 hyaluronan binding protein 4
HOXA7 homeobox A7
HOXB1 homeobox B1
HPX hemopexin
ICA1 islet cell autoantigen 1, 69kDa
IGFBP7 insulin-like growth factor binding protein 7
IL33 interleukin 33
ITPK1 inositol-tetrakisphosphate 1-kinase
JPH3 junctophilin 3
KAT2A K(lysine) acetyltransferase 2A
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KIF1C kinesin family member 1C
KLF12 Kruppel-like factor 12
KLHDC8A kelch domain containing 8A
L1TD1 LINE-1 type transposase domain containing 1
LAG3 lymphocyte-activation gene 3
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC79999 uncharacterized LOC79999
LRTM1 leucine-rich repeats and transmembrane domains 1
MAGEA1 melanoma antigen family A1
MAGEA5 melanoma antigen family A5
MILR1 mast cell immunoglobulin-like receptor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NKX3-2 NK3 homeobox 2
NME5 NME/NM23 family member 5
NOX1 NADPH oxidase 1
NPR1 natriuretic peptide receptor 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
PCDHGA3 protocadherin gamma subfamily A, 3
PDE4D phosphodiesterase 4D, cAMP-specific
PHLDB1 pleckstrin homology-like domain, family B, member 1
PNMAL1 paraneoplastic Ma antigen family-like 1
POU1F1 POU class 1 homeobox 1
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDM9 PR domain containing 9
PRODH2 proline dehydrogenase (oxidase) 2
PSG11 pregnancy specific beta-1-glycoprotein 11
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTBP3 polypyrimidine tract binding protein 3
RAB2A RAB2A, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RET ret proto-oncogene
RFXAP regulatory factor X-associated protein
RIMS2 regulating synaptic membrane exocytosis 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SPON1 spondin 1, extracellular matrix protein
STC1 stanniocalcin 1
SUGP1 SURP and G patch domain containing 1
SYT17 synaptotagmin XVII
TLK1 tousled-like kinase 1
TLR1 toll-like receptor 1
TMEM63A transmembrane protein 63A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TP53I11 tumor protein p53 inducible protein 11
TRIM3 tripartite motif containing 3
TRIM49 tripartite motif containing 49
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
ZNF219 zinc finger protein 219
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADTRP androgen-dependent TFPI-regulating protein
AIM2 absent in melanoma 2
AK5 adenylate kinase 5
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AXIN1 axin 1
C5ORF45 chromosome 5 open reading frame 45
CA9 carbonic anhydrase IX
CASS4 Cas scaffolding protein family member 4
CELP carboxyl ester lipase pseudogene
CLDN11 claudin 11
CLEC2B C-type lectin domain family 2, member B
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRMP1 collapsin response mediator protein 1
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYBRD1 cytochrome b reductase 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EDN1 endothelin 1
ELP6 elongator acetyltransferase complex subunit 6
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM184A family with sequence similarity 184, member A
FBXL15 F-box and leucine-rich repeat protein 15
FGF20 fibroblast growth factor 20
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAS8 growth arrest-specific 8
GBX2 gastrulation brain homeobox 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPR1 G protein-coupled receptor 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAUS6 HAUS augmin-like complex, subunit 6
HPR haptoglobin-related protein
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1462 KIAA1462
KLF13 Kruppel-like factor 13
KRT8P12 keratin 8 pseudogene 12
LENEP lens epithelial protein
LRP3 low density lipoprotein receptor-related protein 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
METTL16 methyltransferase like 16
MMP13 matrix metallopeptidase 13
MOCS3 molybdenum cofactor synthesis 3
MTCP1 mature T-cell proliferation 1
MTERF4 mitochondrial transcription termination factor 4
MTSS1L metastasis suppressor 1-like
MYO15A myosin XVA
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
OLFML2B olfactomedin-like 2B
PACS1 phosphofurin acidic cluster sorting protein 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCDHGB5 protocadherin gamma subfamily B, 5
PGPEP1 pyroglutamyl-peptidase I
PHEX phosphate regulating endopeptidase homolog, X-linked
PLD2 phospholipase D2
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKG2 protein kinase, cGMP-dependent, type II
RGS17 regulator of G-protein signaling 17
RHOBTB1 Rho-related BTB domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNDC3B RUN domain containing 3B
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCPEP1 serine carboxypeptidase 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC16A6 solute carrier family 16, member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SYCP2 synaptonemal complex protein 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLR2 toll-like receptor 2
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAC T cell receptor alpha constant
TRIM45 tripartite motif containing 45
TSPAN8 tetraspanin 8
UGT8 UDP glycosyltransferase 8
UNC119 unc-119 homolog (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
WNT1 wingless-type MMTV integration site family, member 1
ZNF140 zinc finger protein 140
ZNF442 zinc finger protein 442
ZNF675 zinc finger protein 675
ZNF816 zinc finger protein 816