| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the sanguinarine-2927 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARC | activity-regulated cytoskeleton-associated protein |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BAG3 | BCL2-associated athanogene 3 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BMP6 | bone morphogenetic protein 6 |
| CLU | clusterin |
| CREM | cAMP responsive element modulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXADR | coxsackie virus and adenovirus receptor |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EPS8L1 | EPS8-like 1 |
| ESRP1 | epithelial splicing regulatory protein 1 |
| FAM46C | family with sequence similarity 46, member C |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FZD7 | frizzled class receptor 7 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLB1L | galactosidase, beta 1-like |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3A | histone cluster 1, H3a |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3H | histone cluster 1, H3h |
| HIST1H3I | histone cluster 1, H3i |
| HIST1H3J | histone cluster 1, H3j |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4B | histone cluster 1, H4b |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4E | histone cluster 1, H4e |
| HIST1H4J | histone cluster 1, H4j |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER5 | immediate early response 5 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL24 | interleukin 24 |
| INHBA | inhibin, beta A |
| ISG15 | ISG15 ubiquitin-like modifier |
| JUN | jun proto-oncogene |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KLHL25 | kelch-like family member 25 |
| LRRC23 | leucine rich repeat containing 23 |
| MMP1 | matrix metallopeptidase 1 |
| MMP19 | matrix metallopeptidase 19 |
| MRPL18 | mitochondrial ribosomal protein L18 |
| MT1G | metallothionein 1G |
| MT2A | metallothionein 2A |
| MXD1 | MAX dimerization protein 1 |
| NOV | nephroblastoma overexpressed |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCDH9 | protocadherin 9 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| THBS1 | thrombospondin 1 |
| TMEM143 | transmembrane protein 143 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRA2B | transformer 2 beta homolog (Drosophila) |
| TSPAN13 | tetraspanin 13 |
| USPL1 | ubiquitin specific peptidase like 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| AGO1 | argonaute RISC catalytic component 1 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| CBR4 | carbonyl reductase 4 |
| CCDC47 | coiled-coil domain containing 47 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD302 | CD302 molecule |
| CDC7 | cell division cycle 7 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CTPS1 | CTP synthase 1 |
| DCAF6 | DDB1 and CUL4 associated factor 6 |
| DDHD2 | DDHD domain containing 2 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DHCR7 | 7-dehydrocholesterol reductase |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DPYD | dihydropyrimidine dehydrogenase |
| E2F8 | E2F transcription factor 8 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| FAM188A | family with sequence similarity 188, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| FOXJ2 | forkhead box J2 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GCA | grancalcin, EF-hand calcium binding protein |
| GFI1 | growth factor independent 1 transcription repressor |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HMGA2 | high mobility group AT-hook 2 |
| IMPACT | impact RWD domain protein |
| INSIG1 | insulin induced gene 1 |
| INSIG2 | insulin induced gene 2 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KIAA0922 | KIAA0922 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LRRC42 | leucine rich repeat containing 42 |
| LY75 | lymphocyte antigen 75 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase |
| MXI1 | MAX interactor 1, dimerization protein |
| NDRG1 | N-myc downstream regulated 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL12 | nucleolar protein 12 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OXCT1 | 3-oxoacid CoA transferase 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PGRMC2 | progesterone receptor membrane component 2 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| POGK | pogo transposable element with KRAB domain |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| RABL3 | RAB, member of RAS oncogene family-like 3 |
| RARS | arginyl-tRNA synthetase |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RBM38 | RNA binding motif protein 38 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| REEP4 | receptor accessory protein 4 |
| RGS13 | regulator of G-protein signaling 13 |
| RINT1 | RAD50 interactor 1 |
| RPIA | ribose 5-phosphate isomerase A |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| RSBN1 | round spermatid basic protein 1 |
| SACS | sacsin molecular chaperone |
| SEH1L | SEH1-like (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFXN3 | sideroflexin 3 |
| SLA | Src-like-adaptor |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| STK39 | serine threonine kinase 39 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TGM5 | transglutaminase 5 |
| TMEM183A | transmembrane protein 183A |
| TMEM38B | transmembrane protein 38B |
| TMEM45A | transmembrane protein 45A |
| TNF | tumor necrosis factor |
| TRIM8 | tripartite motif containing 8 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| WDR3 | WD repeat domain 3 |
| WT1 | Wilms tumor 1 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
