| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the sanguinarine-4168 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALPK1 | alpha-kinase 1 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ATF3 | activating transcription factor 3 |
| BRS3 | bombesin-like receptor 3 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CALD1 | caldesmon 1 |
| CARD10 | caspase recruitment domain family, member 10 |
| CCKAR | cholecystokinin A receptor |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CHI3L2 | chitinase 3-like 2 |
| CNN3 | calponin 3, acidic |
| COL2A1 | collagen, type II, alpha 1 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CRYAB | crystallin, alpha B |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DAZL | deleted in azoospermia-like |
| DENND5B | DENN/MADD domain containing 5B |
| DLK1 | delta-like 1 homolog (Drosophila) |
| EGR1 | early growth response 1 |
| FAM149A | family with sequence similarity 149, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXO40 | F-box protein 40 |
| FGF18 | fibroblast growth factor 18 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FYB | FYN binding protein |
| FZD8 | frizzled class receptor 8 |
| GCM1 | glial cells missing homolog 1 (Drosophila) |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 |
| GPC3 | glypican 3 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 |
| GRM8 | glutamate receptor, metabotropic 8 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H3B | histone cluster 1, H3b |
| HP | haptoglobin |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| JAM3 | junctional adhesion molecule 3 |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| KIAA0125 | KIAA0125 |
| KIF1C | kinesin family member 1C |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLF13 | Kruppel-like factor 13 |
| KLF6 | Kruppel-like factor 6 |
| KLK13 | kallikrein-related peptidase 13 |
| LAMB4 | laminin, beta 4 |
| LDB3 | LIM domain binding 3 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MID1 | midline 1 |
| MIP | major intrinsic protein of lens fiber |
| MXD1 | MAX dimerization protein 1 |
| NAG18 | NAG18 mRNA |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NKX2-1 | NK2 homeobox 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OR6A2 | olfactory receptor, family 6, subfamily A, member 2 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PRDM9 | PR domain containing 9 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RGCC | regulator of cell cycle |
| RGS2 | regulator of G-protein signaling 2 |
| RPL35A | ribosomal protein L35a |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RUNX1 | runt-related transcription factor 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SPTBN4 | spectrin, beta, non-erythrocytic 4 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TFEB | transcription factor EB |
| TGFB2 | transforming growth factor, beta 2 |
| TPP1 | tripeptidyl peptidase I |
| WIF1 | WNT inhibitory factor 1 |
| ZNF426 | zinc finger protein 426 |
| ZNF721 | zinc finger protein 721 |
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADCY6 | adenylate cyclase 6 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AGO2 | argonaute RISC catalytic component 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP11B | ATPase, class VI, type 11B |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BLNK | B-cell linker |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC85C | coiled-coil domain containing 85C |
| CCP110 | centriolar coiled coil protein 110kDa |
| CES3 | carboxylesterase 3 |
| CRY2 | cryptochrome circadian clock 2 |
| DCP2 | decapping mRNA 2 |
| EFNA3 | ephrin-A3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM169A | family with sequence similarity 169, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GOLGA3 | golgin A3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 |
| ICK | intestinal cell (MAK-like) kinase |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRF6 | interferon regulatory factor 6 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LOC730101 | uncharacterized LOC730101 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCOLN1 | mucolipin 1 |
| MDM4 | MDM4, p53 regulator |
| MGA | MGA, MAX dimerization protein |
| MGC12488 | |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTCP1 | mature T-cell proliferation 1 |
| MXD3 | MAX dimerization protein 3 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NHLRC2 | NHL repeat containing 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL12 | nucleolar protein 12 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RFTN1 | raftlin, lipid raft linker 1 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SACS | sacsin molecular chaperone |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STRN | striatin, calmodulin binding protein |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYCP2 | synaptonemal complex protein 2 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| SYNRG | synergin, gamma |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMEM242 | transmembrane protein 242 |
| TRIM21 | tripartite motif containing 21 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| TULP4 | tubby like protein 4 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VGF | VGF nerve growth factor inducible |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VLDLR | very low density lipoprotein receptor |
| WDR44 | WD repeat domain 44 |
| XK | X-linked Kx blood group |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF106 | zinc finger protein 106 |
| ZNF35 | zinc finger protein 35 |
| ZNF510 | zinc finger protein 510 |
| ZNF629 | zinc finger protein 629 |
| ZNF652 | zinc finger protein 652 |
