| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the santonin-3795 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ABI2 | abl-interactor 2 |
| ACE2 | angiotensin I converting enzyme 2 |
| ACO2 | aconitase 2, mitochondrial |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
| ADRB3 | adrenoceptor beta 3 |
| AJAP1 | adherens junctions associated protein 1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ALPP | alkaline phosphatase, placental |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BMP2 | bone morphogenetic protein 2 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CALB2 | calbindin 2 |
| CALCB | calcitonin-related polypeptide beta |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC121 | coiled-coil domain containing 121 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CFAP74 | cilia and flagella associated protein 74 |
| CFP | complement factor properdin |
| CHAD | chondroadherin |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DIO2 | deiodinase, iodothyronine, type II |
| DTNB | dystrobrevin, beta |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FZD10 | frizzled class receptor 10 |
| GLRA1 | glycine receptor, alpha 1 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GUCA1A | guanylate cyclase activator 1A (retina) |
| IGL | immunoglobulin lambda locus |
| ITGA7 | integrin, alpha 7 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LOC100131532 | uncharacterized LOC100131532 |
| LOXL2 | lysyl oxidase-like 2 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MEGF6 | multiple EGF-like-domains 6 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP11 | matrix metallopeptidase 11 |
| MST1 | macrophage stimulating 1 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NUP188 | nucleoporin 188kDa |
| NUP54 | nucleoporin 54kDa |
| OPRM1 | opioid receptor, mu 1 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PAGE1 | P antigen family, member 1 (prostate associated) |
| PAX2 | paired box 2 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PDLIM5 | PDZ and LIM domain 5 |
| PIGR | polymeric immunoglobulin receptor |
| PIP | prolactin-induced protein |
| POU2F2 | POU class 2 homeobox 2 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRDM10 | PR domain containing 10 |
| PROX1 | prospero homeobox 1 |
| PSCA | prostate stem cell antigen |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RFPL2 | ret finger protein-like 2 |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
| RPL3L | ribosomal protein L3-like |
| RPS3A | ribosomal protein S3A |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAGD | Ras-related GTP binding D |
| RUNX1 | runt-related transcription factor 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERHL2 | serine hydrolase-like 2 |
| SFTPB | surfactant protein B |
| SKIL | SKI-like proto-oncogene |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TDRD12 | tudor domain containing 12 |
| TLR1 | toll-like receptor 1 |
| TLR5 | toll-like receptor 5 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TOX | thymocyte selection-associated high mobility group box |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TTC12 | tetratricopeptide repeat domain 12 |
| TUBA3C | tubulin, alpha 3c |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AKTIP | AKT interacting protein |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANXA10 | annexin A10 |
| ARSB | arylsulfatase B |
| BBC3 | BCL2 binding component 3 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNK | cyclin K |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLSTN3 | calsyntenin 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COBL | cordon-bleu WH2 repeat protein |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EPPK1 | epiplakin 1 |
| EREG | epiregulin |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBRS | fibrosin |
| FGF13 | fibroblast growth factor 13 |
| FGL1 | fibrinogen-like 1 |
| FKRP | fukutin related protein |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GAS2 | growth arrest-specific 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GK3P | glycerol kinase 3 pseudogene |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR19 | G protein-coupled receptor 19 |
| GPR39 | G protein-coupled receptor 39 |
| HIST1H1E | histone cluster 1, H1e |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT54 | intraflagellar transport 54 |
| IPO8 | importin 8 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KLF13 | Kruppel-like factor 13 |
| LAMC3 | laminin, gamma 3 |
| LIPG | lipase, endothelial |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MXD3 | MAX dimerization protein 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NID2 | nidogen 2 (osteonidogen) |
| PADI1 | peptidyl arginine deiminase, type I |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHF14 | PHD finger protein 14 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSENEN | presenilin enhancer gamma secretase subunit |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB36 | RAB36, member RAS oncogene family |
| REEP1 | receptor accessory protein 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SKI | SKI proto-oncogene |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TLR2 | toll-like receptor 2 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM206 | transmembrane protein 206 |
| TRIM45 | tripartite motif containing 45 |
| VGLL3 | vestigial-like family member 3 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XDH | xanthine dehydrogenase |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF415 | zinc finger protein 415 |
| ZNF428 | zinc finger protein 428 |
| ZNF573 | zinc finger protein 573 |
| ZNF671 | zinc finger protein 671 |
| ZNF711 | zinc finger protein 711 |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |