santonin-3795 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the santonin-3795 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABI2 abl-interactor 2
ACE2 angiotensin I converting enzyme 2
ACO2 aconitase 2, mitochondrial
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADRB3 adrenoceptor beta 3
AJAP1 adherens junctions associated protein 1
ALOXE3 arachidonate lipoxygenase 3
ALPP alkaline phosphatase, placental
ARID4B AT rich interactive domain 4B (RBP1-like)
BAAT bile acid CoA:amino acid N-acyltransferase
BMP2 bone morphogenetic protein 2
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C11ORF16 chromosome 11 open reading frame 16
C19ORF73 chromosome 19 open reading frame 73
C7ORF69 chromosome 7 open reading frame 69
CALB2 calbindin 2
CALCB calcitonin-related polypeptide beta
CASS4 Cas scaffolding protein family member 4
CCDC121 coiled-coil domain containing 121
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFAP74 cilia and flagella associated protein 74
CFP complement factor properdin
CHAD chondroadherin
CSF1 colony stimulating factor 1 (macrophage)
CSHL1 chorionic somatomammotropin hormone-like 1
DEFA4 defensin, alpha 4, corticostatin
DIO2 deiodinase, iodothyronine, type II
DTNB dystrobrevin, beta
FAM189A2 family with sequence similarity 189, member A2
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FZD10 frizzled class receptor 10
GLRA1 glycine receptor, alpha 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRM7 glutamate receptor, metabotropic 7
GUCA1A guanylate cyclase activator 1A (retina)
IGL immunoglobulin lambda locus
ITGA7 integrin, alpha 7
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LINC00260 long intergenic non-protein coding RNA 260
LOC100131532 uncharacterized LOC100131532
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LRRN3 leucine rich repeat neuronal 3
MAN1C1 mannosidase, alpha, class 1C, member 1
MBD2 methyl-CpG binding domain protein 2
MEGF6 multiple EGF-like-domains 6
MIER2 mesoderm induction early response 1, family member 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP11 matrix metallopeptidase 11
MST1 macrophage stimulating 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NCF4 neutrophil cytosolic factor 4, 40kDa
NUP188 nucleoporin 188kDa
NUP54 nucleoporin 54kDa
OPRM1 opioid receptor, mu 1
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAGE1 P antigen family, member 1 (prostate associated)
PAX2 paired box 2
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDLIM5 PDZ and LIM domain 5
PIGR polymeric immunoglobulin receptor
PIP prolactin-induced protein
POU2F2 POU class 2 homeobox 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRDM10 PR domain containing 10
PROX1 prospero homeobox 1
PSCA prostate stem cell antigen
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RFPL2 ret finger protein-like 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPL3L ribosomal protein L3-like
RPS3A ribosomal protein S3A
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAGD Ras-related GTP binding D
RUNX1 runt-related transcription factor 1
SAA3P serum amyloid A3 pseudogene
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERHL2 serine hydrolase-like 2
SFTPB surfactant protein B
SKIL SKI-like proto-oncogene
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SPTBN1 spectrin, beta, non-erythrocytic 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TDRD12 tudor domain containing 12
TLR1 toll-like receptor 1
TLR5 toll-like receptor 5
TNNT3 troponin T type 3 (skeletal, fast)
TOX thymocyte selection-associated high mobility group box
TP53I11 tumor protein p53 inducible protein 11
TTC12 tetratricopeptide repeat domain 12
TUBA3C tubulin, alpha 3c

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AKTIP AKT interacting protein
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANXA10 annexin A10
ARSB arylsulfatase B
BBC3 BCL2 binding component 3
BCAS4 breast carcinoma amplified sequence 4
C14ORF93 chromosome 14 open reading frame 93
C16ORF59 chromosome 16 open reading frame 59
C1ORF105 chromosome 1 open reading frame 105
C5ORF42 chromosome 5 open reading frame 42
C7ORF43 chromosome 7 open reading frame 43
CCDC85C coiled-coil domain containing 85C
CCNK cyclin K
CDKL3 cyclin-dependent kinase-like 3
CLCN6 chloride channel, voltage-sensitive 6
CLSTN3 calsyntenin 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COBL cordon-bleu WH2 repeat protein
COPZ2 coatomer protein complex, subunit zeta 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EML4 echinoderm microtubule associated protein like 4
EPPK1 epiplakin 1
EREG epiregulin
ERN2 endoplasmic reticulum to nucleus signaling 2
FBRS fibrosin
FGF13 fibroblast growth factor 13
FGL1 fibrinogen-like 1
FKRP fukutin related protein
FRS2 fibroblast growth factor receptor substrate 2
GAS2 growth arrest-specific 2
GDAP1 ganglioside induced differentiation associated protein 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GK3P glycerol kinase 3 pseudogene
GLS2 glutaminase 2 (liver, mitochondrial)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR19 G protein-coupled receptor 19
GPR39 G protein-coupled receptor 39
HIST1H1E histone cluster 1, H1e
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFT54 intraflagellar transport 54
IPO8 importin 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KLF13 Kruppel-like factor 13
LAMC3 laminin, gamma 3
LIPG lipase, endothelial
LMAN1 lectin, mannose-binding, 1
LRRK1 leucine-rich repeat kinase 1
LYPD3 LY6/PLAUR domain containing 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MRPL44 mitochondrial ribosomal protein L44
MXD3 MAX dimerization protein 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NID2 nidogen 2 (osteonidogen)
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGPEP1 pyroglutamyl-peptidase I
PHF14 PHD finger protein 14
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRB3 proline-rich protein BstNI subfamily 3
PSAT1 phosphoserine aminotransferase 1
PSENEN presenilin enhancer gamma secretase subunit
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB36 RAB36, member RAS oncogene family
REEP1 receptor accessory protein 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
S1PR1 sphingosine-1-phosphate receptor 1
SAYSD1 SAYSVFN motif domain containing 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SKI SKI proto-oncogene
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCEAL2 transcription elongation factor A (SII)-like 2
TFCP2L1 transcription factor CP2-like 1
TLR2 toll-like receptor 2
TM7SF2 transmembrane 7 superfamily member 2
TMEM206 transmembrane protein 206
TRIM45 tripartite motif containing 45
VGLL3 vestigial-like family member 3
WNT10B wingless-type MMTV integration site family, member 10B
XDH xanthine dehydrogenase
ZBTB33 zinc finger and BTB domain containing 33
ZNF37BP zinc finger protein 37B, pseudogene
ZNF415 zinc finger protein 415
ZNF428 zinc finger protein 428
ZNF573 zinc finger protein 573
ZNF671 zinc finger protein 671
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76