| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the santonin-4353 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADORA1 | adenosine A1 receptor |
| AIM1L | absent in melanoma 1-like |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALOX12B | arachidonate 12-lipoxygenase, 12R type |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| APOC1 | apolipoprotein C-I |
| APOE | apolipoprotein E |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATN1 | atrophin 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| ATRNL1 | attractin-like 1 |
| BEST2 | bestrophin 2 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C8B | complement component 8, beta polypeptide |
| CCNJL | cyclin J-like |
| CD2 | CD2 molecule |
| CD84 | CD84 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEP112 | centrosomal protein 112kDa |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLCA2 | chloride channel accessory 2 |
| COL19A1 | collagen, type XIX, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CPA4 | carboxypeptidase A4 |
| CRMP1 | collapsin response mediator protein 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTNS | cystinosin, lysosomal cystine transporter |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DUSP9 | dual specificity phosphatase 9 |
| DUX1 | double homeobox 1 |
| EMCN | endomucin |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FBXO41 | F-box protein 41 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FGF16 | fibroblast growth factor 16 |
| FZD5 | frizzled class receptor 5 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSAP | gamma-secretase activating protein |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HHLA1 | HERV-H LTR-associating 1 |
| HIC2 | hypermethylated in cancer 2 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KIAA0125 | KIAA0125 |
| KLK13 | kallikrein-related peptidase 13 |
| KXD1 | KxDL motif containing 1 |
| LDLR | low density lipoprotein receptor |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRRC31 | leucine rich repeat containing 31 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MMP25 | matrix metallopeptidase 25 |
| MST1 | macrophage stimulating 1 |
| MUC3B | mucin 3B, cell surface associated |
| MXD4 | MAX dimerization protein 4 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NEFM | neurofilament, medium polypeptide |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| OR1A1 | olfactory receptor, family 1, subfamily A, member 1 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PEG10 | paternally expressed 10 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PQLC3 | PQ loop repeat containing 3 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RUNX2 | runt-related transcription factor 2 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SH3BP2 | SH3-domain binding protein 2 |
| SHOX2 | short stature homeobox 2 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) |
| TMEM176A | transmembrane protein 176A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRD | T cell receptor delta locus |
| TRIM15 | tripartite motif containing 15 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ALS2CL | ALS2 C-terminal like |
| B9D2 | B9 protein domain 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCDC68 | coiled-coil domain containing 68 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOC2A | double C2-like domains, alpha |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EGFL7 | EGF-like-domain, multiple 7 |
| FAM204A | family with sequence similarity 204, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXO2 | F-box protein 2 |
| FGF13 | fibroblast growth factor 13 |
| FGF23 | fibroblast growth factor 23 |
| FGL1 | fibrinogen-like 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXI1 | forkhead box I1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3B | histone cluster 1, H3b |
| ICK | intestinal cell (MAK-like) kinase |
| IL17RA | interleukin 17 receptor A |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KLF2 | Kruppel-like factor 2 |
| KLHL28 | kelch-like family member 28 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT24 | keratin 24, type I |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MFAP2 | microfibrillar-associated protein 2 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| OLFML2A | olfactomedin-like 2A |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PADI3 | peptidyl arginine deiminase, type III |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHA6 | protocadherin alpha 6 |
| PCDHB13 | protocadherin beta 13 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE12 | phosphodiesterase 12 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRR4 | proline rich 4 (lacrimal) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RND1 | Rho family GTPase 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RRAGB | Ras-related GTP binding B |
| S100A7 | S100 calcium binding protein A7 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SHPK | sedoheptulokinase |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNTA1 | syntrophin, alpha 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STRN | striatin, calmodulin binding protein |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCHH | trichohyalin |
| TDRD1 | tudor domain containing 1 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR5 | toll-like receptor 5 |
| TPSG1 | tryptase gamma 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| USP20 | ubiquitin specific peptidase 20 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF124 | zinc finger protein 124 |
| ZNF304 | zinc finger protein 304 |
| ZNF696 | zinc finger protein 696 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
