| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the saquinavir-3549 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 |
| ACTN2 | actinin, alpha 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AIM1L | absent in melanoma 1-like |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATN1 | atrophin 1 |
| BDKRB1 | bradykinin receptor B1 |
| BMP4 | bone morphogenetic protein 4 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CAPN15 | calpain 15 |
| CD22 | CD22 molecule |
| CDC14A | cell division cycle 14A |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CES3 | carboxylesterase 3 |
| CLDN17 | claudin 17 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DENND5B | DENN/MADD domain containing 5B |
| DEPDC5 | DEP domain containing 5 |
| DGKI | diacylglycerol kinase, iota |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DSC3 | desmocollin 3 |
| EN2 | engrailed homeobox 2 |
| ESPN | espin |
| FBXO4 | F-box protein 4 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FN1 | fibronectin 1 |
| FOXO4 | forkhead box O4 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FRMD1 | FERM domain containing 1 |
| FRMD4A | FERM domain containing 4A |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPM6A | glycoprotein M6A |
| GPM6B | glycoprotein M6B |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HOMER3 | homer scaffolding protein 3 |
| HRG | histidine-rich glycoprotein |
| IHH | indian hedgehog |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLHL22 | kelch-like family member 22 |
| LCMT2 | leucine carboxyl methyltransferase 2 |
| LEFTY2 | left-right determination factor 2 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTMR7 | myotubularin related protein 7 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NF1 | neurofibromin 1 |
| NOL10 | nucleolar protein 10 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OBSL1 | obscurin-like 1 |
| OPRK1 | opioid receptor, kappa 1 |
| PADI3 | peptidyl arginine deiminase, type III |
| PALM | paralemmin |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLCB2 | phospholipase C, beta 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRAME | preferentially expressed antigen in melanoma |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| QKI | QKI, KH domain containing, RNA binding |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RND1 | Rho family GTPase 1 |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SIX6 | SIX homeobox 6 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STAB2 | stabilin 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM204 | transmembrane protein 204 |
| TOP3B | topoisomerase (DNA) III beta |
| TPSAB1 | tryptase alpha/beta 1 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TUBA3C | tubulin, alpha 3c |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WDR33 | WD repeat domain 33 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZIM2 | zinc finger, imprinted 2 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BTD | biotinidase |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCNK | cyclin K |
| CCNL2 | cyclin L2 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDK3 | cyclin-dependent kinase 3 |
| CDK9 | cyclin-dependent kinase 9 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CFAP44 | cilia and flagella associated protein 44 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CXADR | coxsackie virus and adenovirus receptor |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DMC1 | DNA meiotic recombinase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FKBP5 | FK506 binding protein 5 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| IFT81 | intraflagellar transport 81 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KLHL26 | kelch-like family member 26 |
| KLK5 | kallikrein-related peptidase 5 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MED18 | mediator complex subunit 18 |
| MEIS2 | Meis homeobox 2 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MON1B | MON1 secretory trafficking family member B |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| NBEAL2 | neurobeachin-like 2 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| OLFML2A | olfactomedin-like 2A |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PANX1 | pannexin 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RNF31 | ring finger protein 31 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A4 | S100 calcium binding protein A4 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SHARPIN | SHANK-associated RH domain interactor |
| SIX1 | SIX homeobox 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNHG20 | small nucleolar RNA host gene 20 |
| SNX16 | sorting nexin 16 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3 | stromal antigen 3 |
| STON1 | stonin 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TARP | TCR gamma alternate reading frame protein |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM184B | transmembrane protein 184B |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM13 | tripartite motif containing 13 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF586 | zinc finger protein 586 |
| ZNF652 | zinc finger protein 652 |
| ZNF701 | zinc finger protein 701 |
| ZNF768 | zinc finger protein 768 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
