| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the saquinavir-5770 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| APOC1 | apolipoprotein C-I |
| ARG1 | arginase 1 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATP10A | ATPase, class V, type 10A |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD58 | CD58 molecule |
| CD6 | CD6 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLOCK | clock circadian regulator |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CPZ | carboxypeptidase Z |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CXORF21 | chromosome X open reading frame 21 |
| DCT | dopachrome tautomerase |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FBXO21 | F-box protein 21 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| GGT1 | gamma-glutamyltransferase 1 |
| GK | glycerol kinase |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSN-AS1 | GSN antisense RNA 1 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIST1H2BN | histone cluster 1, H2bn |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOOK1 | hook microtubule-tethering protein 1 |
| HRH4 | histamine receptor H4 |
| IGL | immunoglobulin lambda locus |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| IL12A | interleukin 12A |
| IL1A | interleukin 1, alpha |
| INHBC | inhibin, beta C |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNV2 | potassium channel, voltage gated modifier subfamily V, member 2 |
| KIAA1456 | KIAA1456 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LAMA4 | laminin, alpha 4 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LRRC23 | leucine rich repeat containing 23 |
| LSP1 | lymphocyte-specific protein 1 |
| LUZP4 | leucine zipper protein 4 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAP7D3 | MAP7 domain containing 3 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MED25 | mediator complex subunit 25 |
| MFAP3 | microfibrillar-associated protein 3 |
| MR1 | major histocompatibility complex, class I-related |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYRF | myelin regulatory factor |
| NLRP1 | NLR family, pyrin domain containing 1 |
| OGDHL | oxoglutarate dehydrogenase-like |
| PAX2 | paired box 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PLXNB2 | plexin B2 |
| POU2F2 | POU class 2 homeobox 2 |
| PRM1 | protamine 1 |
| PRPF18 | pre-mRNA processing factor 18 |
| PRSS50 | protease, serine, 50 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SYNGR1 | synaptogyrin 1 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TGM4 | transglutaminase 4 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNRD3 | thioredoxin reductase 3 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZNF529 | zinc finger protein 529 |
| ZNF747 | zinc finger protein 747 |
| ZP2 | zona pellucida glycoprotein 2 (sperm receptor) |
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AXIN1 | axin 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5 | complement component 5 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CLEC2B | C-type lectin domain family 2, member B |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| EGF | epidermal growth factor |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPPK1 | epiplakin 1 |
| FAM127B | family with sequence similarity 127, member B |
| FAM50B | family with sequence similarity 50, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GALT | galactose-1-phosphate uridylyltransferase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR1 | G protein-coupled receptor 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3G | histone cluster 1, H3g |
| HMOX1 | heme oxygenase 1 |
| HOMER2 | homer scaffolding protein 2 |
| IFNA14 | interferon, alpha 14 |
| INO80D | INO80 complex subunit D |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIFC1 | kinesin family member C1 |
| KPTN | kaptin (actin binding protein) |
| LOC257152 | uncharacterized LOC257152 |
| LOC730101 | uncharacterized LOC730101 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MATN3 | matrilin 3 |
| MCM9 | minichromosome maintenance complex component 9 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MXRA8 | matrix-remodelling associated 8 |
| NABP1 | nucleic acid binding protein 1 |
| NDRG4 | NDRG family member 4 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NOL12 | nucleolar protein 12 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE12 | phosphodiesterase 12 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PODXL2 | podocalyxin-like 2 |
| POLH | polymerase (DNA directed), eta |
| RGCC | regulator of cell cycle |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SETBP1 | SET binding protein 1 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TEAD3 | TEA domain family member 3 |
| TMEM53 | transmembrane protein 53 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| XAB2 | XPA binding protein 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF107 | zinc finger protein 107 |
| ZNF141 | zinc finger protein 141 |
| ZNF276 | zinc finger protein 276 |
| ZNF350 | zinc finger protein 350 |
| ZNF76 | zinc finger protein 76 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
