| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the saquinavir-6127 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BIN1 | bridging integrator 1 |
| BMP7 | bone morphogenetic protein 7 |
| BTBD18 | BTB (POZ) domain containing 18 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CAPN9 | calpain 9 |
| CCND1 | cyclin D1 |
| CD1A | CD1a molecule |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CIB2 | calcium and integrin binding family member 2 |
| CLEC4M | C-type lectin domain family 4, member M |
| CLIC5 | chloride intracellular channel 5 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DOPEY1 | dopey family member 1 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EXPH5 | exophilin 5 |
| FAM149A | family with sequence similarity 149, member A |
| FBXO31 | F-box protein 31 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOXE1 | forkhead box E1 |
| GCGR | glucagon receptor |
| GUK1 | guanylate kinase 1 |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IFNA16 | interferon, alpha 16 |
| IL21R | interleukin 21 receptor |
| INO80B | INO80 complex subunit B |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| JAG1 | jagged 1 |
| KIAA0087 | KIAA0087 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLC2 | kinesin light chain 2 |
| KRT81 | keratin 81, type II |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MED6 | mediator complex subunit 6 |
| MEOX2 | mesenchyme homeobox 2 |
| METTL7A | methyltransferase like 7A |
| MFAP3L | microfibrillar-associated protein 3-like |
| MINK1 | misshapen-like kinase 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPTXR | neuronal pentraxin receptor |
| NRF1 | nuclear respiratory factor 1 |
| PAPPA2 | pappalysin 2 |
| PCDH9 | protocadherin 9 |
| PCGF2 | polycomb group ring finger 2 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PER3 | period circadian clock 3 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLBD1 | phospholipase B domain containing 1 |
| PLIN2 | perilipin 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRKCZ | protein kinase C, zeta |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBP4 | retinol binding protein 4, plasma |
| SLAMF7 | SLAM family member 7 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPRR1B | small proline-rich protein 1B |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| ST7L | suppression of tumorigenicity 7 like |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TLN2 | talin 2 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM51 | transmembrane protein 51 |
| TNIK | TRAF2 and NCK interacting kinase |
| TPMT | thiopurine S-methyltransferase |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TULP1 | tubby like protein 1 |
| WWC1 | WW and C2 domain containing 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMYND11 | zinc finger, MYND-type containing 11 |
| ZNF93 | zinc finger protein 93 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASPN | asporin |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CD82 | CD82 molecule |
| CEP170B | centrosomal protein 170B |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLEC2D | C-type lectin domain family 2, member D |
| CNTNAP1 | contactin associated protein 1 |
| COL15A1 | collagen, type XV, alpha 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTRL | chymotrypsin-like |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DENND5B | DENN/MADD domain containing 5B |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPATCH3 | G patch domain containing 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HSPB8 | heat shock 22kDa protein 8 |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA17 | interferon, alpha 17 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0513 | KIAA0513 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIMD2 | LIM domain containing 2 |
| LOXL3 | lysyl oxidase-like 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYRM9 | LYR motif containing 9 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| METRN | meteorin, glial cell differentiation regulator |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MVP | major vault protein |
| NCALD | neurocalcin delta |
| OMG | oligodendrocyte myelin glycoprotein |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PDE12 | phosphodiesterase 12 |
| PDGFD | platelet derived growth factor D |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLA2G3 | phospholipase A2, group III |
| PLD3 | phospholipase D family, member 3 |
| PLP1 | proteolipid protein 1 |
| PNOC | prepronociceptin |
| PODNL1 | podocan-like 1 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PROL1 | proline rich, lacrimal 1 |
| PRR7 | proline rich 7 (synaptic) |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RNF39 | ring finger protein 39 |
| RPGRIP1L | RPGRIP1-like |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SYCP2 | synaptonemal complex protein 2 |
| TAOK1 | TAO kinase 1 |
| TCTN1 | tectonic family member 1 |
| TCTN2 | tectonic family member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TLR8 | toll-like receptor 8 |
| TMEM110 | transmembrane protein 110 |
| TMEM140 | transmembrane protein 140 |
| TMEM212 | transmembrane protein 212 |
| TNRC6B | trinucleotide repeat containing 6B |
| TNS2 | tensin 2 |
| TRIM9 | tripartite motif containing 9 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPK3A | uroplakin 3A |
| WASF3 | WAS protein family, member 3 |
| WDR4 | WD repeat domain 4 |
| ZIC3 | Zic family member 3 |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
