| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the saquinavir-6246 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADCK2 | aarF domain containing kinase 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APP | amyloid beta (A4) precursor protein |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ATP11A | ATPase, class VI, type 11A |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| CABIN1 | calcineurin binding protein 1 |
| CABP2 | calcium binding protein 2 |
| CACTIN | cactin, spliceosome C complex subunit |
| CAPN9 | calpain 9 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CEP162 | centrosomal protein 162kDa |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CORO7 | coronin 7 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DOC2A | double C2-like domains, alpha |
| EPHA1 | EPH receptor A1 |
| FAM134B | family with sequence similarity 134, member B |
| FGF2 | fibroblast growth factor 2 (basic) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GPR182 | G protein-coupled receptor 182 |
| HIRA | histone cell cycle regulator |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HLF | hepatic leukemia factor |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IFT38 | intraflagellar transport 38 |
| IL1R1 | interleukin 1 receptor, type I |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAG1 | jagged 1 |
| KHSRP | KH-type splicing regulatory protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC157562 | uncharacterized LOC157562 |
| LPIN2 | lipin 2 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAP4 | microtubule-associated protein 4 |
| MCOLN1 | mucolipin 1 |
| MEOX2 | mesenchyme homeobox 2 |
| MYOF | myoferlin |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF1 | neurofibromin 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDCD2 | programmed cell death 2 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) |
| PLA2G3 | phospholipase A2, group III |
| PLAT | plasminogen activator, tissue |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLXNA1 | plexin A1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB5B | RAB5B, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RANBP1 | RAN binding protein 1 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| REST | RE1-silencing transcription factor |
| RNF122 | ring finger protein 122 |
| RNF17 | ring finger protein 17 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa |
| SGCE | sarcoglycan, epsilon |
| SIRPA | signal-regulatory protein alpha |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SRCAP | Snf2-related CREBBP activator protein |
| STOML1 | stomatin (EPB72)-like 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBE3A | ubiquitin protein ligase E3A |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR62 | WD repeat domain 62 |
| WIZ | widely interspaced zinc finger motifs |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| AGBL5 | ATP/GTP binding protein-like 5 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BAK1 | BCL2-antagonist/killer 1 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CFD | complement factor D (adipsin) |
| CLDN15 | claudin 15 |
| CLDN4 | claudin 4 |
| CXORF56 | chromosome X open reading frame 56 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DENND4C | DENN/MADD domain containing 4C |
| EHD3 | EH-domain containing 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERCC5 | excision repair cross-complementation group 5 |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FASTKD5 | FAST kinase domains 5 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPALPP1 | GPALPP motifs containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H2AFJ | H2A histone family, member J |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HPSE | heparanase |
| ICK | intestinal cell (MAK-like) kinase |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| IREB2 | iron-responsive element binding protein 2 |
| ISOC1 | isochorismatase domain containing 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIF18A | kinesin family member 18A |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAGEF1 | melanoma antigen family F1 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAP9 | microtubule-associated protein 9 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED24 | mediator complex subunit 24 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MRPL46 | mitochondrial ribosomal protein L46 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| ORC3 | origin recognition complex, subunit 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PARPBP | PARP1 binding protein |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PMM1 | phosphomannomutase 1 |
| POMZP3 | POM121 and ZP3 fusion |
| PRMT7 | protein arginine methyltransferase 7 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB23 | RAB23, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RANBP6 | RAN binding protein 6 |
| RARS | arginyl-tRNA synthetase |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RTFDC1 | replication termination factor 2 domain containing 1 |
| RWDD3 | RWD domain containing 3 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SNX16 | sorting nexin 16 |
| STBD1 | starch binding domain 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| THAP7 | THAP domain containing 7 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM115 | transmembrane protein 115 |
| TRIM25 | tripartite motif containing 25 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| UBQLN4 | ubiquilin 4 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WDR18 | WD repeat domain 18 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF180 | zinc finger protein 180 |
| ZNF184 | zinc finger protein 184 |
| ZNF33B | zinc finger protein 33B |
| ZNF668 | zinc finger protein 668 |
