sca Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A spinocerebellar degeneration that is characterized by degeneration of the cerebellum leading to loss of muscle coordination. (Human Disease Ontology, DOID_1441)
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Genes

35 genes co-occuring with the biological term sca in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AFG3L2 AFG3-like AAA ATPase 2
ATXN1 ataxin 1
ATXN2 ataxin 2
ATXN3 ataxin 3
ATXN7 ataxin 7
BDNF brain-derived neurotrophic factor
CASQ2 calsequestrin 2 (cardiac muscle)
FGF14 fibroblast growth factor 14
FOXH1 forkhead box H1
G6PD glucose-6-phosphate dehydrogenase
GRM1 glutamate receptor, metabotropic 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
LPCAT1 lysophosphatidylcholine acyltransferase 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PDE9A phosphodiesterase 9A
PDGFA platelet-derived growth factor alpha polypeptide
PDYN prodynorphin
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PRKCG protein kinase C, gamma
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
SSTR5 somatostatin receptor 5
TCF12 transcription factor 12
TCF3 transcription factor 3
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14